Evidence map›Paper›PMID 30108415›Full record

ArticleBioinformation2018

Insights from the sequence similarity of Zika virus proteins with the Human nerve proteins.

Prasanna Marsakatla, Sujai Suneetha, Joshua Lee, Paari Dominic Swaminathan, Logeshwaran Vasudevan, Rachael Supriya, Lavanya Moses Suneetha

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioinformation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Prasanna MarsakatlaCODEWEL Nireekshana ACET, Narayanaguda, Hyderabad -500029, Telangana, India.
Sujai SuneethaCODEWEL Nireekshana ACET, Narayanaguda, Hyderabad -500029, Telangana, India.
Joshua LeeYork University, Department of Science, 4700 Keele St, Toronto, ON M3J 1P3, Canada.
Paari Dominic SwaminathanLSU Health Sciences Center, Center for Cardiovascular Diseases and Sciences Shreveport, LA, USA.
Logeshwaran VasudevanPresidency College, Department of Zoology, Chennai-05, India.
Rachael SupriyaCODEWEL Nireekshana ACET, Narayanaguda, Hyderabad -500029, Telangana, India.
Lavanya Moses SuneethaCODEWEL Nireekshana ACET, Narayanaguda, Hyderabad -500029, Telangana, India.
Narayana Health · INLouisiana State University Health Sciences Center Shreveport · USPresidency University · INYork University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Massive peptide sharing between the Zika virus polyprotein and host tissue proteins could elicit significant host-pathogen interactions and cross-reactions leading to autoimmune diseases. This study found similarities in the Zika V proteins and human nerve tissue proteins. 63 human nerve proteins were screened for similarities with the Zika V of which Neuromodulin, Nestin, Galanin, Bombesin, Calcium-binding protein were found to have similarities to the Zika V poly protein C at different sequence regions. These sequence similarities could be significant in regulating pathogenic interactions/autoimmunity, as Polyprotein C is known to be a virulent factor.

Indexed as

BioinformaticsBLASTBombesinCalcium-binding proteinGalaninNerve tissue proteinsNestinNeuromodulinNeuropathogenesisZika V

Identifiers

PMID30108415
PMCPMC6077820
OpenAlexW2810892457

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.