Evidence map›Paper›PMID 30108337›Full record

Trial reportInternational journal of impotence research2019

Low-intensity shockwave therapy for erectile dysfunction in kidney transplant recipients. A prospective, randomized, double blinded, sham-controlled study with evaluation by penile Doppler ultrasonography.

Kleiton G R Yamaçake, Felipe Carneiro, Jose Cury, Rodolfo Lourenço, Peter C Françolin, Affonso C Piovesan, Miguel Srougi, Willian C Nahas, Ioannis M Antonopoulos

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in International journal of impotence research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 4 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 4 syntheses or guidelines pooled it, 61 citations in OpenAlex.

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  19. Novel Emerging Therapies for Erectile Dysfunction.The world journal of men's health · 2021
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Kleiton G R YamaçakeDivision of Urology, Renal Transplantation Unit, University of São Paulo Medical School, São Paulo, Brazil. kleiton_med91@yahoo.com.br.
Felipe CarneiroDivision of Radiology, University of São Paulo Medical School, São Paulo, Brazil.
Jose CuryDivision of Urology, Renal Transplantation Unit, University of São Paulo Medical School, São Paulo, Brazil.
Rodolfo LourençoDivision of Urology, Renal Transplantation Unit, University of São Paulo Medical School, São Paulo, Brazil.
Peter C FrançolinDivision of Radiology, University of São Paulo Medical School, São Paulo, Brazil.
Affonso C PiovesanDivision of Urology, Renal Transplantation Unit, University of São Paulo Medical School, São Paulo, Brazil.
Miguel SrougiRenal Transplantation Unit, Division of Urology, University of São Paulo Medical School, São Paulo, Brazil.
Willian C NahasRenal Transplantation Unit, Division of Urology, University of São Paulo Medical School, São Paulo, Brazil.
Ioannis M AntonopoulosDivision of Urology, Renal Transplantation Unit, University of São Paulo Medical School, São Paulo, Brazil.
Universidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo study the efficacy of Low intensity Extracorporeal Shockwave Therapy (Li- ESWT) for the treatment of erectile dysfunction (ED) in kidney transplanted men.

methodsTwenty men (mean age = 53.7 years) were selected. This was a double-blinded, prospective, randomized, sham-controlled trial. The ESWT protocol was based in a 2 treatment sessions per week for 3 weeks. The sham treatment was performed using the same device replacing the effective probe for one that emits zero energy. Baseline and follow-up assessment was performed with International Index of Erectile Function Questionnaire (IIEF) score and Erection Hardness Score (EHS) after 1, 4 and 12 months. Penile Doppler was performed before and after treatment.

resultsA total of 20 patients were recruited, 10 patients in each group. Baseline scores were similar. The mean EHS in after 1 month were 2.5 ± 0.85 (Li-EWST) and 2.4 ± 0.7 (Sham therapy), p = 0.724 . After 4 months it was 2.4 ± 0.7 and 2.6 ± 0.84, p = 0,0004 (between the moments) . The baseline IIEF score was 14.9 ± 3(Sham Theraphy) and 10.9 ± 5.1 (Li-EWST). The mean IIEF score after 1 month was 15.6 ± 6.1 (Li-EWST) and 16.6 ± 5.4 (Sham therapy). The mean IIEF score after 4 months was 17.2 ± 5.7 (Li-EWST) and 16.5 ± 5 (Sham therapy), p < 0.0001 (between the moments). IIEF score improvement was higher than 5 in 70% (ranged from 0-10) and in 10% (ranged from 1-14) in Li-ESWT and Sham groups, respectively. The mean change in IIEF score after 12 months was 4.8 in Li-ESWT group .Penile Doppler parameters were similar between groups and did not present improvements.

conclusionsLi-ESWT is a treatment with clinical efficacy. Despite evidences suggesting neoagiogenesis, our short protocol had no impact in penile Doppler parameters.

Indexed as

Kidney TransplantationUltrasonic TherapyDouble-Blind MethodErectile DysfunctionHumansMaleMiddle AgedPenile ErectionPenisProspective StudiesSeverity of Illness IndexTreatment OutcomeUltrasonography, Doppler

Identifiers

PMID30108337
OpenAlexW2887251558

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.