ArticleScientific reports2018
Nanohydroxyapatite/polyamide 66 strut subsidence after one-level corpectomy: underlying mechanism and effect on cervical neurological function.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 12 citations in OpenAlex.
- Three-dimensional printed artificial vertebral body versus titanium mesh cage and nanohydroxyapatite/polyamide-66 cage in anterior cervical corpectomy and fusion: a retrospective cohort study with a minimum 5-year follow-up.Journal of orthopaedic surgery and research · 2026Observational
- Biomaterials for vertebral body repair: interior augmentation and total replacement-a literature review of bone fusion outcomes in clinical studies.Journal of spine surgery (Hong Kong) · 2026Review
- L1 vertebral body replacement using 3D-printed polylactic acid bioimplants:Journal of spine surgery (Hong Kong) · 2025Article
- Risk factors of early subsidence of 3D-printed artificial vertebral body following single-level anterior cervical corpectomy and fusion (ACCF): retrospective study of 98 patients.Journal of orthopaedic surgery and research · 2025Article
- Long-Term Outcomes of Nano-Hydroxyapatite/Polyamide 66 Strut in Thoracolumbar Burst Fractures.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- A novel nanohydroxyapatite/polyamide 66 strut for reducing subsidence after one-level anterior cervical corpectomy and fusion: a finite-element study.European journal of medical research · 2024Article
- A novel nanohydroxyapatite/polyamide-66 cage for reducing the subsidence rate after single-level anterior cervical discectomy and fusion: a comparative study of 7-year follow-up.Journal of orthopaedic surgery and research · 2023Article
- Anterior 1-2 Level Cervical Corpectomy and Fusion for Degenerative Cervical Disease: A Retrospective Study With Lordotic Porous Tantalum Cages. Long-Term Changes in Sagittal Alignment and Their Clinical and Radiological Implications After Cage Subsidence.International journal of spine surgery · 2022Article
- Comparison of radiological and clinical outcomes of 3D-printed artificial vertebral body with Titanium mesh cage in single-level anterior cervical corpectomy and fusion: A meta-analysis.Frontiers in surgery · 2022Review
- Enhancement of the bone-implant interface by applying a plasma-sprayed titanium coating on nanohydroxyapatite/polyamide66 implants in a rabbit model.Scientific reports · 2021Article
- Comparative Analysis of 3D-Printed Artificial Vertebral Body Versus Titanium Mesh Cage in Repairing Bone Defects Following Single-Level Anterior Cervical Corpectomy and Fusion.Medical science monitor : international medical journal of experimental and clinical research · 2021Article
- Imaging evaluation of nano-hydroxyapatite/polyamide 66 strut in cervical construction after 1-level corpectomy: a retrospective study of 520 patients.European journal of medical research · 2020Article
- In vivo evaluation of porous nanohydroxyapatite/polyamide 66 struts in a goat cervical fusion model.Scientific reports · 2020Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to investigate n-HA/PA66 strut subsidence after one-level in Anterior cervical corpectomy decompression and fusion (ACCF) and its effect on treatment outcomes to better understand the underlying mechanism and related risk factors. In total, 56 patients undergoing ACCF using n-HA/PA66 struts were analysed retrospectively. After a 12-month follow-up, the height of the fused segments and fused intervertebral heights were measured, the neurological findings were evaluated using the Japanese Orthopedic Association (JOA) and axial pain was assessed using a Visual Analogue Scale(VAS). Subsidence was defined as a decrease in the height of the fused segments or the fused intervertebral body greater than 3 mm compared with that on postoperative day one, and all patients were assigned to the n-HA/PA66 strut subsidence and control groups. In total, 45 patients experienced n-HA/PA66 strut subsidence during the postoperative (3 ± 2.42/3.11 ± 2.01) months. No significant differences were observed in sex, age, hospitalization time, surgical haemorrhage,bone mineral density (BMD), or height in the n-HA/PA66 strut group. The JOA and VAS of neck pain in the control group improved more than those in the subsidence group, suggesting that subsidence might be correlated with poor improvement of neurological function. In conclusion, n-HA/PA66 strut subsidence is a common complication after ACCF, and the reduced height of the postoperative fused segments and the height reduction in the postoperative fused intervertebral bodies are independent risk factors of n-HA/PA66 strut subsidence.
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