Evidence map›Paper›PMID 30108274›Full record

ArticleScientific reports2018

Oxidative stress decreases the redox ratio and folate content in the gut microbe, Enterococcus durans (MTCC 3031).

Steffi Jose, Prerna Bhalla, G K Suraishkumar

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. World journal of gastroenterology · 2024
    Article
  5. Article
  6. Sub-1.4 cmNature · 2023
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Folate metabolism modifies chromosomal damage induced by 1,3-butadiene: results from a match-up study in China and in vitro experiments.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2021
    Article
  12. Review
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Steffi JoseDepartment of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences building Indian Institute of Technology Madras, Chennai, 600036, India.
Prerna BhallaDepartment of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences building Indian Institute of Technology Madras, Chennai, 600036, India.
G K SuraishkumarDepartment of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences building Indian Institute of Technology Madras, Chennai, 600036, India. gk@iitm.ac.in.ORCID 0000-0002-6521-4494
Indian Institute of Technology Madras · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gut microbiome plays an important role in determining the effectiveness of cancer therapy. The composition of the microbiome is crucial to maintain good digestive health in the host, and to prevent and treat colorectal cancers. Most cancer therapies employ oxidative stress, which disturbs the redox status of the cell, and consequently affect growth, reductive biosynthesis and cell death. Therefore, oxidative stress can undesirably affect the gut microbiome. Hence, it is important to understand the impact of oxidative stress on gut bacteria to devise effective treatment strategies. The current study induces oxidative stress in the model gut bacterium Enterococcus durans (MTCC 3031) with menadione and H

Indexed as

Antineoplastic AgentsColorectal NeoplasmsEnterococcusFolic AcidFolic Acid DeficiencyGastrointestinal MicrobiomeHumansHydrogen PeroxideOxidation-ReductionOxidative StressTreatment OutcomeVitamin K 3Antineoplastic AgentsFolic AcidHydrogen PeroxideVitamin K 3

Identifiers

PMID30108274
PMCPMC6092354
OpenAlexW2885116975

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.