Evidence map›Paper›PMID 30108180›Full record

ArticleGenome research2018

Natural genetic variation in

Arwen W Gao, Mark G Sterken, Jelmi Uit de Bos, Jelle van Creij, Rashmi Kamble, Basten L Snoek, Jan E Kammenga, Riekelt H Houtkooper

Open access · bronzeAbstract read
In one paragraph

Article in Genome research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 36 citations in OpenAlex.

  1. Genetic mapping of lifespan and mitochondrial stress response inbioRxiv : the preprint server for biology · 2025
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. High-content phenotypic analysis ofbioRxiv : the preprint server for biology · 2024
    Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Genetic Variation inMicroorganisms · 2020
    Review
  16. Dissecting the eQTL Micro-Architecture inFrontiers in genetics · 2020
    Article
  17. WormQTL2: an interactive platform for systems genetics in Caenorhabditis elegans.Database : the journal of biological databases and curation · 2020
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Arwen W Gao *Laboratory Genetic Metabolic Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam Gastroenterology and Metabolism, 1105 AZ Amsterdam, The Netherlands.
Mark G Sterken *Laboratory of Nematology, Wageningen University and Research, 6708 PB, Wageningen, The Netherlands.
Jelmi Uit de BosLaboratory Genetic Metabolic Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam Gastroenterology and Metabolism, 1105 AZ Amsterdam, The Netherlands.
Jelle van CreijLaboratory of Nematology, Wageningen University and Research, 6708 PB, Wageningen, The Netherlands.
Rashmi KambleLaboratory Genetic Metabolic Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam Gastroenterology and Metabolism, 1105 AZ Amsterdam, The Netherlands.
Basten L SnoekLaboratory of Nematology, Wageningen University and Research, 6708 PB, Wageningen, The Netherlands.
Jan E KammengaLaboratory of Nematology, Wageningen University and Research, 6708 PB, Wageningen, The Netherlands.
Riekelt H HoutkooperLaboratory Genetic Metabolic Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam Gastroenterology and Metabolism, 1105 AZ Amsterdam, The Netherlands.ORCID 0000-0001-9961-0842
Amsterdam Neuroscience · NLWageningen University & Research · NL

Funding

European Research Council 638290
6 · The paper itself

Abstract

Metabolic homeostasis is sustained by complex biological networks that respond to nutrient availability. Genetic and environmental factors may disrupt this equilibrium, leading to metabolic disorders, including obesity and type 2 diabetes. To identify the genetic factors controlling metabolism, we performed quantitative genetic analysis using a population of 199 recombinant inbred lines (RILs) in the nematode

Indexed as

Polymorphism, GeneticQuantitative Trait LociAmino AcidsAnimalsCaenorhabditis elegansFatty AcidsMetabolomeAmino AcidsFatty Acids

Identifiers

PMID30108180
PMCPMC6120624
OpenAlexW2767949589

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.