Evidence map›Paper›PMID 30108051›Full record

ArticleDisease models & mechanisms2018

Soluble endoglin regulates expression of angiogenesis-related proteins and induction of arteriovenous malformations in a mouse model of hereditary hemorrhagic telangiectasia.

Eunate Gallardo-Vara, Simon Tual-Chalot, Luisa M Botella, Helen M Arthur, Carmelo Bernabeu

Open access · goldAbstract read
In one paragraph

Article in Disease models & mechanisms, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 34 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Systemic Cytokines in Retinopathy of Prematurity.Journal of personalized medicine · 2023
    Review
  5. Article
  6. Article
  7. Review
  8. TGF-β superfamily co-receptors in cancer.Developmental dynamics : an official publication of the American Association of Anatomists · 2022
    Review
  9. Article
  10. Article
  11. Article
  12. Cerebrovascular development: mechanisms and experimental approaches.Cellular and molecular life sciences : CMLS · 2021
    Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Role of soluble endoglin in BMP9 signaling.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Eunate Gallardo-VaraCentro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas (CSIC), and Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), 28040 Madrid, Spain.
Simon Tual-ChalotInstitute of Genetic Medicine, Centre for Life, Newcastle University, Newcastle NE1 3BZ, UK.
Luisa M BotellaCentro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas (CSIC), and Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), 28040 Madrid, Spain.
Helen M ArthurInstitute of Genetic Medicine, Centre for Life, Newcastle University, Newcastle NE1 3BZ, UK.
Carmelo BernabeuCentro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas (CSIC), and Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), 28040 Madrid, Spain bernabeu.c@cib.csic.es.ORCID 0000-0002-1563-6162
Consejo Superior de Investigaciones Científicas · ESCentre for Life · GB

Funding

British Heart Foundation PG/14/86/31177British Heart Foundation RG/12/2/29416
6 · The paper itself

Abstract

Endoglin is a transmembrane glycoprotein expressed in vascular endothelium that plays a key role in angiogenesis. Mutations in the endoglin gene (

Indexed as

Gene Expression RegulationAnimalsArteriovenous MalformationsBiomarkersCell MovementDisease Models, AnimalEndoglinHumansHuman Umbilical Vein Endothelial CellsLungMice, KnockoutModels, BiologicalNeovascularization, PathologicRetinaSolubilityTelangiectasia, Hereditary HemorrhagicBiomarkersEndoglinAngiogenesisAVMEndoglinEndothelial cellsHHTTGF-β

Identifiers

PMID30108051
PMCPMC6176985
OpenAlexW2886585929

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.