Evidence map›Paper›PMID 30107833›Full record

Trial reportBMC public health2018

Vaginal washing and lubrication among female sex workers in the Mexico-US border region: implications for the development of vaginal PrEP for HIV prevention.

Heather A Pines, Shirley J Semple, Steffanie A Strathdee, Craig W Hendrix, Alicia Harvey-Vera, Pamina M Gorbach, Carlos Magis-Rodríguez, Gustavo Martinez, Thomas L Patterson

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02447484 (Texting Intervention to Sustain HIV Prevention in Women in High-drug-use Contexts), which is not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02447484 nacompletednot on this map

Texting Intervention to Sustain HIV Prevention in Women in High-drug-use Contexts

TypeinterventionalSponsorUniversity of California, San DiegoRan2015 to 2021Enrolled600ConditionsHIV, Syphilis, Gonorrhea, ChlamydiaArmsMujer Segura Siempre, General Health Message Texts
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Heather A PinesDepartment of Medicine, University of California, San Diego, 9500 Gilman Drive, MC 0507, La Jolla, CA, 92093, USA. hpines@ucsd.edu.ORCID http://orcid.org/0000-0002-7173-1981
Shirley J SempleDepartment of Psychiatry, University of California, San Diego, 9500 Gilman Drive, MC 0680, La Jolla, CA, 92093, USA.
Steffanie A StrathdeeDepartment of Medicine, University of California, San Diego, 9500 Gilman Drive, MC 0507, La Jolla, CA, 92093, USA.
Craig W HendrixDepartment of Medicine, Johns Hopkins University, 600 N. Wolfe Street, Baltimore, MD, 21287, USA.
Alicia Harvey-VeraDepartment of Medicine, University of California, San Diego, 9500 Gilman Drive, MC 0507, La Jolla, CA, 92093, USA.
Pamina M GorbachDepartment of Epidemiology, University of California, Los Angeles, 650 Charles E Young Drive S, BOX 951772, Los Angeles, CA, 90095, USA.
Carlos Magis-RodríguezCentro Nacional para la Prevención y Control del VIH/SIDA (CENSIDA) Ministry of Health, Mexico City, Mexico.
Gustavo MartinezFederacion Mexicana de Asociaciones Privadas, Ciudad Juarez, Chihuahua, Mexico.
Thomas L PattersonDepartment of Psychiatry, University of California, San Diego, 9500 Gilman Drive, MC 0680, La Jolla, CA, 92093, USA.
University of California San Diego · USCentro Medico Nacional Siglo XXI · MXJohns Hopkins University · USUniversity of California, Los Angeles · US

Funding

VirologyP30AI036214 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI David Mitchell Smith · 1994 to 2026
$78.4M
Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Richard E. Chaisson · 2012 to 2026
$67.0M
UCLA Rapid, Relevant, Rigorous Implementation Science HubP30MH058107 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Nina Thawata Harawa · 1997 to 2026
$53.5M
Tissue pharmacology imaging and modelingU19AI113127 · NIAID · JOHNS HOPKINS UNIVERSITY · PI MCGOWAN, IAN MICHAEL · 2014 to 2018
$20.7M
Texting intervention to sustain HIV prevention in women in high-drug-use contextsR01DA039071 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PATTERSON, THOMAS L. · 2015 to 2019
$3.3M
Sexual Networks and HIV Transmission Clusters among Substance Using MSMK01DA040543 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PINES, HEATHER ALISA · 2015 to 2019
$901k
National Institute on Drug Abuse K01DA040543National Institute on Drug Abuse R01DA039071National Institutes of Health P30 AI036214NIAID NIH HHS P30 AI036214NIAID NIH HHS P30 AI094189NIAID NIH HHS U19 AI113127NIDA NIH HHS K01 DA040543NIDA NIH HHS R01 DA039071NIMH NIH HHS P30 MH058107
6 · The paper itself

Abstract

backgroundTo assess the potential acceptability and inform the development of behaviorally-congruent vaginal douche- or gel-based HIV pre-exposure prophylaxis (PrEP) products, we examined vaginal washing and lubrication practices among female sex workers (FSWs) in Tijuana and Ciudad Juarez, two northern Mexico cities bordering the United States (US).

methodsTwo hundred and ninety-five HIV-negative FSWs (145 Tijuana; 150 Ciudad Juarez) enrolled in a behavioral HIV prevention intervention trial completed surveys assessing vaginal washing and lubrication practices, as well as motivators and barriers to performing each practice. Logistic regression was used to identify potential predictors of each practice in the past month.

resultsIn the past month, vaginal washing was performed by 56 and 22% of FSWs in Tijuana and Ciudad Juarez (p <  0.0001), respectively, while vaginal lubrication was performed by 64 and 45% of FSWs in Tijuana and Ciudad Juarez (p = 0.001), respectively. Vaginal washing was positively associated with living in Tijuana (adjusted odds ratio [AOR] = 4.35, 95% confidence interval [CI]: 2.60-7.30), older age (AOR = 1.04 per year, 95% CI: 1.01-1.06), and vaginal lubrication (AOR = 2.99, 95% CI: 1.67-5.35), while it was negatively associated with being born in the same state as the study site (AOR = 0.50, 95% CI: 0.31-0.82), earning a monthly income ≥3500 pesos (AOR = 0.53, 95% CI: 0.28-1.00), and hazardous alcohol consumption (AOR = 0.56, 95% CI: 0.33-0.95). Vaginal lubrication was positively associated with living in Tijuana (AOR = 2.21, 95% CI: 1.37-3.54) and vaginal washing (AOR = 2.91, 95% CI: 1.64-5.18), while it was negatively associated with being born in the same state as the study site (AOR = 0.47, 95% CI: 0.29-0.75).

conclusionsThe moderate and high prevalence of vaginal washing and lubrication, respectively, suggest behaviorally-congruent, multi-purpose, vaginal douche- and gel-based PrEP products that simultaneously address FSWs' needs and prevent HIV infection may be acceptable to many FSWs along the Mexico-US border. Future product development and implementation should also consider the link between vaginal washing and lubrication to ensure existing practices do not undermine vaginal PrEP product effectiveness.

trial registrationClincialTrials.gov ( NCT02447484 ).

Indexed as

LubricationPre-Exposure ProphylaxisAdultFemaleHIV InfectionsHumansMexicoMiddle AgedSex WorkersSurveys and QuestionnairesUnited StatesVaginal DouchingFemale sex workersHIVMexicoPre-exposure prophylaxisVaginal practices

Identifiers

PMID30107833
PMCPMC6092873
OpenAlexW2885647458

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.