ArticleAmerican journal of hypertension2019
Dietary Phosphorus and Ambulatory Blood Pressure in African Americans: The Jackson Heart Study.
Article in American journal of hypertension, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Dietary phosphorus intake and blood pressure in adults: a systematic review of randomized trials and prospective observational studies.The American journal of clinical nutrition · 2019Pooled it
- Is phosphate burden an under-recognized driver of apparent treatment-resistant hypertension in CKD?Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- High-Phosphate-Induced Hypertension: The Pathogenic Role of Fibroblast Growth Factor 23 (FGF23) Signaling in Sympathetic Nervous System Activation.International journal of molecular sciences · 2026Review
- Elevated phosphate levels in CKD - a direct threat for the heart.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025Review
- Association between dietary phosphate intake and skeletal muscle energetics in adults without cardiovascular disease.Journal of applied physiology (Bethesda, Md. : 1985) · 2024Article
- Estimation of dietary intake of sodium, potassium, phosphorus and protein in healthy Indian population and patients with chronic kidney disease.Frontiers in nutrition · 2024Article
- A Review of Current Evidence on the Relationship between Phosphate Metabolism and Metabolic Syndrome.Nutrients · 2022Review
- Article
- Bioavailability of phosphorus and kidney function in the Jackson Heart Study.The American journal of clinical nutrition · 2022Article
- Article
- High-phosphorus diet controlled for sodium elevates blood pressure in healthy adults via volume expansion.Journal of clinical hypertension (Greenwich, Conn.) · 2021Article
- The association of dietary phosphorus with blood pressure: results from a secondary analysis of the PREMIER trial.Journal of human hypertension · 2020Article
- Phosphate, the forgotten mineral in hypertension.Current opinion in nephrology and hypertension · 2019Review
Corrections and comments
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Authors and funding
15 authors at 7 institutions in 1 country.
Funding
Abstract
backgroundHigher dietary phosphorus is associated with left ventricular hypertrophy and mortality, which are blood pressure (BP)-related outcomes. For this reason, we hypothesized that dietary phosphorus may be associated with adverse clinic and ambulatory BP patterns.
methodsOur study included 973 African American adults enrolled in the Jackson Heart Study (2000-2004) with 24-hour ambulatory BP monitoring (ABPM) data at baseline. We quantified dietary phosphorus from a validated Food Frequency Questionnaire as follows: (i) absolute daily intake, (ii) ratio of phosphorus-to-protein intake, (iii) phosphorus density, and (iv) energy-adjusted phosphorus intake. Using multivariable linear regression, we determined associations between dietary phosphorus intake and systolic blood pressure (SBP), diastolic blood pressure (DBP), and pulse pressure in clinic and over daytime, nighttime, and 24-hour periods from ABPM. Extent of nocturnal BP dipping was also assessed. Using logistic regression, we modeled relationships between dietary phosphorus intake and clinically relevant qualitative BP phenotypes, such as masked, sustained, or white-coat hypertension and normotension.
resultsThere were no statistically significant associations between phosphorus intake and SBP or pulse pressure in adjusted models. Most metrics of higher phosphorus intake were associated with lower daytime, nighttime, and clinic DBP. Higher phosphorus intake was not associated with clinic or ABPM-defined hypertension overall, but most metrics of higher phosphorus intake were associated with lower odds of sustained hypertension compared to sustained normotension, white-coat hypertension, and masked hypertension. There were no associations between dietary phosphorus and nocturnal BP dipping.
conclusionsThese data do not support a role for higher phosphorus intake and higher BP in African Americans.
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Registered trials
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