ArticleACS applied materials & interfaces2018
Diatom Microbubbler for Active Biofilm Removal in Confined Spaces.
Article in ACS applied materials & interfaces, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Unlocking miniature brilliance: micro/nanorobots for advanced dental theranostics.Journal of nanobiotechnology · 2026Review
- Surface versus Nanocatalyst-Induced Matrix Bubbles Govern Temperature-Dependent Biofilm Removal.ACS applied materials & interfaces · 2026Article
- Microbubble-Controlled Delivery of Biofilm-Targeting Nanoparticles to Treat MRSA Infection.Advanced functional materials · 2025Article
- Self-Powered Oxygen Microbubble Generator for Decontamination of Anaerobic Biofilm-Fouled Bioimplants.ACS biomaterials science & engineering · 2025Article
- Micro-Nano Bubbles: A New Field of Eco-Friendly Cleaning.Nanomaterials (Basel, Switzerland) · 2025Review
- Biofilm comes back: Controlling regrowth by mitigating the cell-matrix interaction.Chemical engineering journal (Lausanne, Switzerland : 1996) · 2025Article
- Biofilm removal effect of diatom complex on 3D printed denture base resin.Scientific reports · 2024Article
- Biohybrid Microalgae Robots: Design, Fabrication, Materials, and Applications.Advanced materials (Deerfield Beach, Fla.) · 2024Review
- Antimicrobial efficacy of self-locomotive manganese oxide nanozyme-doped diatom microbubbler on orthodontic brackets in vitro.BMC oral health · 2023Article
- Removal effect ofHeliyon · 2022Article
- Biofilms: Formation, Research Models, Potential Targets, and Methods for Prevention and Treatment.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Review
- Manganese Oxide Nanozyme-Doped Diatom for Safe and Efficient Treatment of Peri-Implantitis.ACS applied materials & interfaces · 2022Article
- Quenching Epigenetic Drug Resistance Using Antihypoxic Microparticles in Glioblastoma Patient-Derived Chips.Advanced healthcare materials · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
Bacterial biofilms form on and within many living tissues, medical devices, and engineered materials, threatening human health and sustainability. Removing biofilms remains a grand challenge despite tremendous efforts made so far, particularly when they are formed in confined spaces. One primary cause is the limited transport of antibacterial agents into extracellular polymeric substances (EPS) of the biofilm. In this study, we hypothesized that a microparticle engineered to be self-locomotive with microbubbles would clean a structure fouled by biofilm by fracturing the EPS and subsequently improving transports of the antiseptic reagent. We examined this hypothesis by doping a hollow cylinder-shaped diatom biosilica with manganese oxide (MnO
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.