ArticleNeurology. Clinical practice2013
Vestibular signs of thiamine deficiency during the early phase of suspected Wernicke encephalopathy.
Article in Neurology. Clinical practice, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.
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Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 64 citations in OpenAlex.
- VOR gain of lateral semicircular canal using video head impulse test in acute unilateral vestibular hypofunction: A systematic review.Frontiers in neurology · 2022Pooled it
- Clinical value of the video head impulse test in patients with vestibular neuritis: a systematic review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021Pooled it
- Astrocytopathy in Wernicke Encephalopathy and Neuromyelitis Optica Spectrum Disorder. Pathogenic Differences With Occasional Clinical and Neuroimaging Overlap. A Review.Current neurology and neuroscience reports · 2026Review
- Acute Vertigo, Dizziness and Imbalance in the Emergency Department-Beyond Stroke and Acute Unilateral Vestibulopathy-A Narrative Review.Brain sciences · 2025Review
- Analysis of Benign Paroxysmal Positional Vertigo Cases in the Posterior Canal at a Tertiary Care Facility.Journal of pharmacy & bioallied sciences · 2025Article
- [The diagnostic strategy, procedure and pathway for acute vestibular syndrome SCD].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2025Article
- Upbeat nystagmus: a clinical and pathophysiological review.Frontiers in neurology · 2025Review
- Evidence for the differential efficacy of yaw and pitch gaze stabilization mechanisms in people with multiple sclerosis.Experimental brain research · 2024Article
- Wernicke encephalopathy induced by glucose infusion: A case report and literature review.Heliyon · 2024Article
- An atypical presentation of Wernicke-Korsakoff encephalopathy mimicking a left hemispheric stroke: case report.Frontiers in psychiatry · 2024Article
- Cerebellar ataxia, neuropathy and vestibular areflexia syndrome (CANVAS): diagnostic contribution of vestibular function tests.BMJ case reports · 2023Article
- Generalized vestibular hyporeflexia and chronic upbeat nystagmus due to thiamine deficiency.Journal of neurology · 2023Article
- A review of the geometrical basis and the principles underlying the use and interpretation of the video head impulse test (vHIT) in clinical vestibular testing.Frontiers in neurology · 2023Review
- Current concepts in acute vestibular syndrome and video-oculography.Current opinion in neurology · 2022Review
- The pharmacological treatment of acute vestibular syndrome.Frontiers in neurology · 2022Review
- A Case Report of Wernicke's Encephalopathy Associated With Schizophrenia.Frontiers in psychiatry · 2021Article
- Isolated Pulvinar/Hockey Stick Sign in Nonalcoholic Wernicke's Encephalopathy.The American journal of case reports · 2020Review
- The Use of Video-Head Impulse Test in Different Head Positions in Vertical Nystagmus and Ataxia Associated with Probable Thiamine Deficiency.Cerebellum (London, England) · 2020Article
- Article
- Consensus Paper. Cerebellar Reserve: From Cerebellar Physiology to Cerebellar Disorders.Cerebellum (London, England) · 2020Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Non-encephalopathic presentations of CNS thiamine deficiency may be difficult to diagnose. We describe neuro-otologic findings of Wernicke syndrome in 5 patients with vestibular manifestations. Diagnosis was confirmed by low serum levels, response to replacement, and brain MRI to exclude other causes. All had bilaterally abnormal horizontal head impulse vestibulo-ocular reflex (VOR) responses and pathologic gaze-evoked nystagmus, without encephalopathy. After thiamine replacement, 4 had total resolution of vestibular and oculomotor findings. Novel findings included 2 patients whose VOR function improved within minutes of IV repletion and 1 whose recovery was documented by serial quantitative recordings. Early diagnosis of Wernicke by examining vestibular reflexes and prompt IV treatment might prevent encephalopathy and other neurologic or systemic complications of thiamine depletion.
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Registered trials
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