ReviewJournal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society2018
Acute Management of Optic Neuritis: An Evolving Paradigm.
Review in Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Differential diagnosis and clinical predictors in suspected optic neuritis.Japanese journal of ophthalmology · 2026Article
- Demographic and Epidemiological Profile of Optic Neuritis in Colombia: A Retrospective Study Using Data from the Comprehensive Information System for Social Protection.Neuro-ophthalmology (Aeolus Press) · 2026Article
- Applications of Machine Learning-Driven Molecular Models for Advancing Ophthalmic Precision Medicine.Bioengineering (Basel, Switzerland) · 2025Review
- Toward curing neurological autoimmune disorders: Biomarkers, immunological mechanisms, and therapeutic targets.Neuron · 2025Review
- Effects of intravenous pulse methylprednisolone in neuromyelitis optica during the acute phase.Annals of clinical and translational neurology · 2024Article
- Visual Function Improvement after Plasma Exchange Therapy for Acute Optic Neuritis in Neuromyelitis Optica Spectrum Disorders: Case Series and Review.Diagnostics (Basel, Switzerland) · 2024Review
- An update on optic neuritis.Journal of neurology · 2023Article
- Visual Outcomes Following Plasma Exchange for Optic Neuritis: An International Multicenter Retrospective Analysis of 395 Optic Neuritis Attacks.American journal of ophthalmology · 2023Article
- MRI pattern in acute optic neuritis: Comparing multiple sclerosis, NMO and MOGAD.The neuroradiology journal · 2023Article
- Overview of diet and autoimmune demyelinating optic neuritis: a narrative review.Immunometabolism (Cobham, Surrey) · 2023Review
- Predictors of Glucocorticoid Use for Acute Optic Neuritis in the United States, 2005-2019.Ophthalmic epidemiology · 2023Article
- Contemporary management challenges in seropositive NMOSD.Journal of neurology · 2022Article
- Treatment and Relapse Prevention of Typical and Atypical Optic Neuritis.International journal of molecular sciences · 2022Review
- The changing landscape of optic neuritis: a narrative review.Journal of neurology · 2022Review
- Application of the International Interocular Difference Thresholds into Practice: Localising the Patient Experience.Neuro-ophthalmology (Aeolus Press) · 2022Article
- Immune checkpoint inhibitor-associated ophthalmic adverse events: current understanding of its mechanisms, diagnosis, and management.International journal of ophthalmology · 2022Review
- Variation in Evolving Optic Neuritis.Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society · 2021Article
- Fampridine improves acute optic neuritis contributing to a long-lasting recovery of nerve function.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021Article
- Article
- Steroid-Resistant Double-Seronegative Optic Neuritis Responds Favorably to Plasma Exchange.Cureus · 2021Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The current management of acute optic neuritis (ON) is focused on expediting visual recovery through the use of high-dose intravenous corticosteroids. The recent identification of specific autoantibodies associated with central nervous system inflammatory disorders has provided novel insights into immune targets and mechanisms that impact the prognosis, treatment, and recurrence of ON. Therefore, neurologists and ophthalmologists need to be aware of clinical, laboratory, and imaging findings that may provide important clues to the etiology of ON and the potential need for aggressive management. Moving forward, rapid and accurate diagnosis of inflammatory ON will likely be critical for implementing clinical care that optimizes short-term and long-term therapeutic outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.