Trial reportThe American journal on addictions2018
Gender differences in demographic and clinical characteristics of patients with opioid use disorder entering a comparative effectiveness medication trial.
Trial report in The American journal on addictions, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Opioid agonist treatment for people who are dependent on pharmaceutical opioids.The Cochrane database of systematic reviews · 2022Pooled it
- Clinical and psychosocial outcomes by sex among individuals prescribed buprenorphine-naloxone (BUP-NX) or extended-release naltrexone (XR-NTX) for opioid use disorder.The American journal on addictions · 2023Trial
- Gender differences among criminal justice-involved persons living with HIV interested in extended-release naltrexone treatment.Substance abuse · 2021Trial
- Barriers and Facilitators to Sexual and Reproductive Healthcare for Women in Opioid Use Disorder Recovery: Perspectives from Recovery Healthcare Professionals.Healthcare (Basel, Switzerland) · 2026Article
- Understanding barriers and facilitators to women's recovery from opioid use disorder: A focus group study.Journal of social work practice in the addictions · 2026Article
- Gender-specific addiction research needed now more than ever: Reflections from 25 years of the NIDA Clinical Trials Network Gender Special Interest Group.Journal of substance use and addiction treatment · 2025Article
- Gender and Overdose Risk Factors Among Clients Entering Residential Treatment for Opioid Use.Drug and alcohol review · 2025Article
- Social Safety Net Programs: The Relationship With Drug Treatment Among Women.American journal of preventive medicine · 2025Article
- Outcome of Buprenorphine maintenance treatment among Indian females with opioid dependence: Report from a tertiary addiction treatment center.Indian journal of psychiatry · 2025Article
- Sex Differences in Opioid Misuse among Adults with Chronic Lower Back Pain: The Roles of Negative Affect and Related Transdiagnostic Factors.Journal of substance use · 2025Article
- Observational
- Perspectives and experiences with sleep and recovery among women receiving buprenorphine for opioid use disorder.PLOS mental health · 2025Article
- Predicting buprenorphine adherence among patients with opioid use disorder in primary care settings.BMC primary care · 2024Article
- Digital health interventions to support women with opioid use disorder: A scoping review.Drug and alcohol dependence · 2024Article
- Protocol for harmonization of randomized trials testing the addition of behavioral therapy to buprenorphine for opioid use disorder.Drug and alcohol dependence reports · 2024Article
- The lived experiences and treatment needs of women with opioid use disorder and posttraumatic stress symptoms: A mixed methods study.Journal of substance use and addiction treatment · 2024Article
- The co-creation and evaluation of a recovery community center bundled model to build recovery capital through the promotion of reproductive health and justice.Addiction research & theory · 2024Article
- Co-occurring psychiatric disorders and disparities in buprenorphine utilization in opioid use disorder: An analysis of insurance claims.Drug and alcohol dependence reports · 2023Article
- Article
- The representation of females in clinical trials for substance use disorder conducted in the United States (2010-19).Addiction (Abingdon, England) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
BACKGROUND &
objectivesWe investigated gender differences in individuals with opioid use disorder (OUD) receiving inpatient services and entering a randomized controlled trial comparing extended-release naltrexone to buprenorphine.
methodsParticipants (N = 570) provided demographic, substance use, and psychiatric information.
resultsWomen were significantly younger, more likely to identify as bisexual, live with a sexual partner, be financially dependent, and less likely employed. Women reported significantly greater psychiatric comorbidity and risk behaviors, shorter duration but similar age of onset of opioid use. DISCUSSION/
conclusionsFindings underscore economic, psychiatric, and infection vulnerability among women with OUD. SCIENTIFIC SIGNIFICANCE: Interventions targeting these disparities should be explored, as women may face complicated treatment initiation, retention, and recovery. (Am J Addict 2018;27:465-470).
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.