Evidence map›Paper›PMID 30106057›Full record

ArticleNeural regeneration research2018

Effect of Graphene Nanoribbons (TexasPEG) on locomotor function recovery in a rat model of lumbar spinal cord transection.

C-Yoon Kim, William K A Sikkema, Jin Kim, Jeong Ah Kim, James Walter, Raymond Dieter, Hyung-Min Chung, Andrea Mana, James M Tour, Sergio Canavero

Open access · goldAbstract read
In one paragraph

Article in Neural regeneration research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

C-Yoon KimDepartment of Stem Cell Biology, School of Medicine, Konkuk University; Department of Laboratory Animal Medicine, College of Veterinary Medicine, Seoul National University, Seoul, Korea.
William K A SikkemaDepartment of Chemistry, Department of Materials Science and NanoEngineering, and The NanoCarbon Center, Rice University, Houston, TX, USA.
Jin KimDepartment of Laboratory Animal Medicine, College of Veterinary Medicine, Seoul National University, Seoul, Korea.
Jeong Ah KimBiomedical Omics Group, Korea Basic Science Institute, Cheongju-si, Chungbuk, Korea.
James WalterResearch Service, Hines Veterans Administration Hospital, Hines, IL, USA.
Raymond DieterResearch Service, Hines Veterans Administration Hospital, Hines, IL, USA.
Hyung-Min ChungDepartment of Stem Cell Biology, School of Medicine, Konkuk University, Seoul, Korea.
Andrea ManaHEAVEN/GEMINI International Collaborative Group, Turin, Italy.
James M TourDepartment of Chemistry, Department of Materials Science and NanoEngineering, and The NanoCarbon Center, Rice University, Houston, TX, USA.
Sergio CanaveroHEAVEN/GEMINI International Collaborative Group, Turin, Italy.
Edward Hines, Jr. VA Hospital · USKonkuk University · KRKorea Basic Science Institute · KRRice University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A sharply transected spinal cord has been shown to be fused under the accelerating influence of membrane fusogens such as polyethylene glycol (PEG) (GEMINI protocol). Previous work provided evidence that this is in fact possible. Other fusogens might improve current results. In this study, we aimed to assess the effects of PEGylated graphene nanoribons (PEG-GNR, and called "TexasPEG" when prepared as 1wt% dispersion in PEG600) versus placebo (saline) on locomotor function recovery and cellular level in a rat model of spinal cord transection at lumbar segment 1 (L

Indexed as

GEMINIgraphene nanoribbonsnerve regenerationspinal cord fusionspinal cord transfectionTexasPEG

Identifiers

PMID30106057
PMCPMC6108198
OpenAlexW2887982448

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.