ArticleEchocardiography (Mount Kisco, N.Y.)2018
Diastolic dysfunction in tetralogy of Fallot: Comparison of echocardiography with catheterization.
Article in Echocardiography (Mount Kisco, N.Y.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- End-Diastolic Forward Flow and Restrictive Physiology in Repaired Tetralogy of Fallot: A Systematic Review and Meta-Analysis.Journal of the American Heart Association · 2022Pooled it
- Anti-obesity medications in adults with congenital heart disease: a comprehensive review and expert clinical recommendations.European heart journal. Quality of care & clinical outcomes · 2026Review
- Long-Term Effects of Right Ventricular Pressure and Volume Overload: A Comparative Analysis in an Ovine Model.Journal of clinical medicine · 2026Article
- From repair to right heart failure: Understanding the evolving landscape in tetralogy of fallot.Heart failure reviews · 2025Review
- Addressing Diastolic Dysfunction in the Congenital Heart Population.Current cardiology reports · 2025Review
- Atrial Right-to-Left Shunting After Tetralogy of Fallot Repair Is Associated With Improved Atrial Function and Shorter Hospital Length of Stay: An Echocardiographic Cohort Study.Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography · 2025Article
- Validation of noninvasive indices of right ventricular diastolic function. Simultaneous echocardiography and pressure-volume catheterization studies.Cardiovascular ultrasound · 2025Article
- Right and left ventricular filling in adult patients with repaired tetralogy of fallot: a 4D flow MRI study.The international journal of cardiovascular imaging · 2025Article
- Assessment of right ventricular diastolic function in pediatric patients with repaired tetralogy of Fallot by cardiovascular magnetic resonance and echocardiography.European radiology · 2024Article
- Repaired Tetralogy of Fallot: Have We Understood the Right Timing of PVR?Journal of clinical medicine · 2024Review
- Association of cardiovascular magnetic resonance diastolic indices with arrhythmia in repaired Tetralogy of Fallot.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023Article
- The right ventricle in tetralogy of Fallot: adaptation to sequential loading.Frontiers in pediatrics · 2023Review
- Right atrial function early after tetralogy of Fallot repair.The international journal of cardiovascular imaging · 2022Article
- Effect of Loading Changes on the Intraventricular Pressure Measured by Color M-Mode Echocardiography in Rats.Diagnostics (Basel, Switzerland) · 2021Article
- Detection of persistent systolic and diastolic abnormalities in asymptomatic pediatric repaired tetralogy of Fallot patients with preserved ejection fraction: a CMR feature tracking study.European radiology · 2021Article
- The Utility of Intraventricular Pressure Gradient for Early Detection of Chemotherapy-Induced Subclinical Cardiac Dysfunction in Dogs.Animals : an open access journal from MDPI · 2021Article
- Right Ventricular Diastolic Performance in Patients With Chronic Thromboembolic Pulmonary Hypertension Assessed by Echocardiography.Frontiers in cardiovascular medicine · 2021Article
- Impact of right atrium dimension on adverse outcome after pulmonary valve replacement in repaired Tetralogy of Fallot patients.The international journal of cardiovascular imaging · 2020Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundRight ventricular (RV) systolic dysfunction has been associated with adverse outcomes in tetralogy of Fallot (TOF). However, the role and etiology of diastolic dysfunction remain incompletely defined. We assessed the association between traditional echocardiographic measures of diastolic function with catheter-based RV end-diastolic pressure (RVEDP) and identified clinical characteristics independently associated with diastolic dysfunction.
methodsSingle-center, retrospective cohort study of surgically repaired TOF patients undergoing cardiac catheterization with echocardiograms within 3 months prior to the catheterization. Tricuspid inflow and tissue Doppler measurements (E/A, E/e', and deceleration time) defined diastolic dysfunction, graded as impaired relaxation, pseudonormal, or restrictive physiology. Regression analyses tested associations between echocardiographic parameters, RVEDP, and clinical characteristics.
resultsNinety-four subjects were included. Catheterization age was 8.9 years (interquartile range 4.4, 15.9). RVEDP was 9.5 ± 2.5 mm Hg. Sixty-one (65%) subjects had echocardiographic evidence of diastolic dysfunction. RVEDP was not associated with echocardiographic parameters of diastolic function (grade of dysfunction, E/e', or E/A). Higher RVEDP was associated with larger right atrial and RV end-diastolic area, independently of weight and degree of pulmonary or tricuspid regurgitation, though was not associated with indexed right atrial or RV end-diastolic area. Greater number of interim procedures was associated with higher RVEDP, E/e', and the presence of diastolic dysfunction by echocardiography.
conclusionsDiastolic dysfunction, as determined by echocardiography-derived and catheter-based (RVEDP) measures, is prevalent in this TOF population. These measures are not associated with each other; therefore, echocardiographic parameters of diastolic function are not reflective of RVEDP. The development of noninvasive parameters that correlate with filling pressures is required.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.