Evidence map›Paper›PMID 30105650›Full record

ArticleNeuromolecular medicine2018

Neuroprotective Effect of Hydrogen Sulfide in Hyperhomocysteinemia Is Mediated Through Antioxidant Action Involving Nrf2.

Mohit Kumar, Rajat Sandhir

Abstract read
PubMed Publisher
In one paragraph

Article in Neuromolecular medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
  2. Transsulfuration Pathway Products and HInternational journal of molecular sciences · 2025
    Review
  3. Review
  4. Hydrogen Sulfide (HCurrent neuropharmacology · 2022
    Review
  5. Review
  6. Article
  7. Plasma hydrogen sulfide: A biomarker of Alzheimer's disease and related dementias.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2021
    Article
  8. Hydrogen Sulfide Reverses LPS-Induced Behavioral Deficits by Suppressing Microglial Activation and Promoting M2 Polarization.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2021
    Article
  9. Review
  10. Homocysteine and Mitochondria in Cardiovascular and Cerebrovascular Systems.International journal of molecular sciences · 2020
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Mohit KumarDepartment of Biochemistry, Basic Medical Science Block-II, Sector-25, Panjab University, Chandigarh, 160014, India.
Rajat SandhirDepartment of Biochemistry, Basic Medical Science Block-II, Sector-25, Panjab University, Chandigarh, 160014, India. sandhir@pu.ac.in.
Panjab University · IN

Funding

Department of Bio-Technology (DBT), Govt. of India, New Delhi BT/361/NE/TBP/2012University Grants Commission (UGC), New Delhi [F.17-7(J)/2004(SA-1)]
6 · The paper itself

Abstract

Homocysteine (Hcy) is a sulfur-containing amino acid derived from methionine metabolism. Elevated plasma Hcy levels (> 15 µM) result in a condition called hyperhomocysteinemia (HHcy), which is an independent risk factor in the development of various neurodegenerative disorders. Reactive oxygen species (ROS) produced by auto-oxidation of Hcy have been implicated in HHcy-associated neurological conditions. Hydrogen sulfide (H

Indexed as

AcetylcholinesteraseAnimalsAntioxidantsCerebral CortexCognition DisordersHippocampusHomocysteineHydrogen SulfideHyperhomocysteinemiaLipid PeroxidationMaleMaze LearningNeuroprotective AgentsNF-E2-Related Factor 2Oxidation-ReductionOxidative StressAcetylcholinesteraseAntioxidantsHomocysteineHydrogen SulfideNeuroprotective AgentsNfe2l2 protein, ratNF-E2-Related Factor 2OxidoreductasesReactive Oxygen SpeciesAntioxidantHomocysteineHydrogen sulfideMemoryNrf2Oxidative stress

Identifiers

PMID30105650
OpenAlexW2886483921

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.