Evidence map›Paper›PMID 30105521›Full record

ArticleMolecular imaging and biology2019

Combined Early and Late [

M Hohberg, C Kobe, P Täger, J Hammes, M Schmidt, F Dietlein, M Wild, A Heidenreich, A Drzezga, M Dietlein

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular imaging and biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 29 citations in OpenAlex.

  1. SUVMolecular imaging and biology · 2020
    Trial
  2. Review
  3. ACS pharmacology & translational science · 2025
    Article
  4. Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024
    Article
  5. Diagnostic value of dual-time pointAbdominal radiology (New York) · 2024
    Article
  6. The superior detection rate of total-body [European journal of nuclear medicine and molecular imaging · 2024
    Article
  7. First-in-human study of PSMA-targeting agent, [European journal of nuclear medicine and molecular imaging · 2024
    Article
  8. Article
  9. Total-body [European journal of nuclear medicine and molecular imaging · 2023
    Article
  10. Article
  11. Multi-timepoint imaging with PSMA-targeted [Annals of nuclear medicine · 2023
    Article
  12. Evaluation of [EJNMMI research · 2022
    Article
  13. Article
  14. Article
  15. Review
  16. EJNMMI physics · 2020
    Article
  17. Theranostics · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

M HohbergDepartment of Nuclear Medicine, University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany. Melanie.Hohberg@uk-koeln.de.ORCID 0000-0002-8128-9058
C KobeDepartment of Nuclear Medicine, University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
P TägerDepartment of Nuclear Medicine, University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
J HammesDepartment of Nuclear Medicine, University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
M SchmidtDepartment of Nuclear Medicine, University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
F DietleinDepartment of Nuclear Medicine, University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
M WildDepartment of Nuclear Medicine, University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
A HeidenreichCancer Center Cologne, University Hospital of Cologne, Cologne, Germany.
A DrzezgaDepartment of Nuclear Medicine, University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
M DietleinDepartment of Nuclear Medicine, University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
University Hospital Cologne · DEDana-Farber Cancer Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeOur aim was to evaluate the benefit of early (1 h post-injection (p.i.)) and late (3 h p.i.) [ PROCEDURES: Seventy patients with BCR of the PCa and prostate-specific antigen (PSA) levels of less than 2.0 μg/l were subjected to [

resultsForty-four of the 70 patients thus examined were interpreted as PSMA-positive in early and/or late scans while 26 remained without suspicion of PSMA tracer uptake. A total of 70 suspicious lesions were analyzed. Ten tumor-suspicious lesions from seven different patients were better or exclusively visible in the late measurements while three tumor-suspicious lesions from three different patients were better or exclusively visible in the early images. A validation by follow-up data was possible for 11 of these 13 additionally detected lesions. In direct comparison between early and late imaging, the mean SUV

conclusionsThe time period between injection and data acquisition influences the detection rate of [

Indexed as

Positron-Emission TomographyAgedAged, 80 and overEdetic AcidFollow-Up StudiesHumansMaleMiddle AgedNeoplasm Recurrence, LocalPositron Emission Tomography Computed TomographyProstate-Specific AntigenProstatic NeoplasmsEdetic AcidN,N'-bis(2-hydroxy-5-(ethylene-beta-carboxy)benzyl)ethylenediamine N,N'-diacetic acidProstate-Specific Antigen[68Ga]PSMA-HBED-CCEarly and late scansLesion detectabilityPETPSMA

Identifiers

PMID30105521
OpenAlexW2887408256

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.