Evidence map›Paper›PMID 30105405›Full record

ArticleParasitology research2018

Population structures of Leishmania infantum and Leishmania tropica the causative agents of kala-azar in Southwest Iran.

Mohammad Amin Ghatee, Hossein Mirhendi, Mehdi Karamian, Walter R Taylor, Iraj Sharifi, Massood Hosseinzadeh, Zahra Kanannejad

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In one paragraph

Article in Parasitology research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Cutaneous leishmaniasis in Afghanistan.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2025
    Review
  4. Article
  5. Article
  6. Genetic Diversity and Population Structure ofPathogens (Basel, Switzerland) · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 3 countries.

Mohammad Amin GhateeCellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, Iran. ghateea1980@gmail.com.
Hossein MirhendiDepartment of Parasitology and Mycology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Mehdi KaramianCellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran.
Walter R TaylorMahidol Oxford Tropical Medicine Research Unit, Bangkok, Thailand.
Iraj SharifiLeishmaniasis Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Massood HosseinzadehDepartment of Pathology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Zahra KanannejadDepartment of Immunology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Shiraz University of Medical Sciences · IRBirjand University of Medical Sciences · IRIsfahan University of Medical Sciences · IRKerman University of Medical Sciences · IRUniversity of Oxford · GBYasuj University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Visceral leishmaniasis (VL) is endemic in Iran and is caused predominantly by Leishmania infantum, but L. tropica is emerging as an important cause. We studied the intra-species population structure of Leishmania spp. causing VL in southwest Iran by sequence analysis of the internal transcribed spacer (ITS) 1 of DNA samples from 29 bone marrow aspiration smears. L. infantum (n = 25) and L. tropica (n = 4) were identified, consisting of 10 and three ITS1 sequence types (STs), respectively. Compared to GenBank ITS1 STs, our L. infantum parasites displayed high heterogeneity but less heterogeneity compared than northwest Iranian isolates. VL affects mostly nomadic populations in southwest Iran, and their mobility may explain partly the L. infantum heterogeneity. The VL causing L. tropica was also genetically heterogeneous but genetically indistinguishable from L. tropica strains causing anthroponotic cutaneous leishmaniasis from southwest Iran.

Indexed as

AdolescentAdultAnimalsBase SequenceChildChild, PreschoolDNA, IntergenicFemaleHumansInfantInfant, NewbornIranLeishmania infantumLeishmaniasis, CutaneousLeishmaniasis, VisceralLeishmania tropicaDNA, IntergenicIranLeishmania infantumLeishmania tropicaPopulation structureVisceral leishmaniasis

Identifiers

PMID30105405
OpenAlexW2885503402

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.