ArticleJournal of vision2018
Spatial summation in the human fovea: Do normal optical aberrations and fixational eye movements have an effect?
Article in Journal of vision, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed.
- Repeatability of Foveal Sensitivity Measured Using Adaptive Optics Microperimetry.Translational vision science & technology · 2026Article
- An image-computable spatio-chromatic receptive field model of the midget retinal ganglion cell mosaic across the retina.Journal of computational neuroscience · 2026Article
- Non-uniform signal pooling across the foveola.Current biology : CB · 2025Article
- Neural network assisted annotation and analysis tool to study in-vivo foveolar cone photoreceptor topography.Scientific reports · 2025Article
- Extended-period AOSLO imaging in the living human retina without pupil dilation: a feasibility study.Biomedical optics express · 2024Article
- Unique yellow shifts for small and brief stimuli in the central retina.Journal of vision · 2024Article
- Investigating the Spatiotemporal Summation of Perimetric Stimuli in Dry Age-Related Macular Degeneration.Translational vision science & technology · 2023Article
- Spatiotemporal summation of perimetric stimuli in healthy observers.Journal of vision · 2023Article
- Twenty-five years of clinical applications using adaptive optics ophthalmoscopy [Invited].Biomedical optics express · 2023Review
- Repeatability and reciprocity of the cone optoretinogram.Biomedical optics express · 2022Article
- The Relationship Between Visual Sensitivity and Eccentricity, Cone Density and Outer Segment Length in the Human Foveola.Investigative ophthalmology & visual science · 2021Article
- Color, Pattern, and the Retinal Cone Mosaic.Current opinion in behavioral sciences · 2019Article
- Visual Function at the Atrophic Border in Choroideremia Assessed with Adaptive Optics Microperimetry.Ophthalmology. Retina · 2019Article
- Eye tracking-based estimation and compensation of chromatic offsets for multi-wavelength retinal microstimulation with foveal cone precision.Biomedical optics express · 2019Article
- Probing Computation in the Primate Visual System at Single-Cone Resolution.Annual review of neuroscience · 2019Review
- Modeling visual performance differences 'around' the visual field: A computational observer approach.PLoS computational biology · 2019Article
- The spectral identity of foveal cones is preserved in hue perception.Journal of vision · 2018Article
- Foveal Crowding Resolved.Scientific reports · 2018Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Psychophysical inferences about the neural mechanisms supporting spatial vision can be undermined by uncertainties introduced by optical aberrations and fixational eye movements, particularly in fovea where the neuronal grain of the visual system is fine. We examined the effect of these preneural factors on photopic spatial summation in the human fovea using a custom adaptive optics scanning light ophthalmoscope that provided control over optical aberrations and retinal stimulus motion. Consistent with previous results, Ricco's area of complete summation encompassed multiple photoreceptors when measured with ordinary amounts of ocular aberrations and retinal stimulus motion. When both factors were minimized experimentally, summation areas were essentially unchanged, suggesting that foveal spatial summation is limited by postreceptoral neural pooling. We compared our behavioral data to predictions generated with a physiologically-inspired front-end model of the visual system, and were able to capture the shape of the summation curves obtained with and without pre-retinal factors using a single postreceptoral summing filter of fixed spatial extent. Given our data and modeling, neurons in the magnocellular visual pathway, such as parasol ganglion cells, provide a candidate neural correlate of Ricco's area in the central fovea.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.