ArticleEndoscopy international open2018
Peroral endoscopic myotomy is effective and safe in non-achalasia esophageal motility disorders: an international multicenter study.
Article in Endoscopy international open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03904004 (Impact of Peroral Endoscopic Myotomy and Other Treatments for Oesophageal Motility Disorders on Bolus Transport and Gastro-oesophageal Reflux. The pFlow Study), which is not on this map. Cited by 43 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Impact of Peroral Endoscopic Myotomy and Other Treatments for Oesophageal Motility Disorders on Bolus Transport and Gastro-oesophageal Reflux. The pFlow Study
Who cites it
43 citing papers in PubMed, 3 syntheses or guidelines pooled it, 117 citations in OpenAlex.
- Esophageal and Oropharyngeal Dysphagia: Clinical Recommendations From the United European Gastroenterology and European Society for Neurogastroenterology and Motility.United European gastroenterology journal · 2025Guideline
- Efficacy and safety of per-oral endoscopic myotomy in non-achalasia esophageal motility disorders: a systematic review and meta-analysis.Esophagus : official journal of the Japan Esophageal Society · 2024Pooled it
- Clinical efficacy of per-oral endoscopic myotomy (POEM) for spastic esophageal disorders: a systematic review and meta-analysis.Surgical endoscopy · 2020Pooled it
- Presence of type 1 hiatal hernia affects the clinical efficacy of per-oral endoscopic myotomy.Surgical endoscopy · 2025Article
- Impact of hiatal hernia on periprocedural outcomes following peroral endoscopic myotomy: a nationwide retrospective study.Surgical endoscopy · 2025Article
- Comparing peroral endoscopic myotomy and laparoscopic Heller myotomy for esophageal motility disorders: Nationwide cohort study.Endoscopy international open · 2025Article
- Real-life management of nonobstructive esophageal dysphagia: analysis of a prospective multicentric Portuguese cohort.Therapeutic advances in gastroenterology · 2025Article
- Esophageal Per-Oral Endoscopic Myotomy (E-POEM): Future Directions and Perspectives.Current gastroenterology reports · 2024Review
- Peroral endoscopic myotomy for hypercontractile (Jackhammer) esophagus: A retrospective multicenter series with long-term follow-up.United European gastroenterology journal · 2024Article
- Esophagogastric Junction Outflow Obstruction (EGJOO): A Manometric Phenomenon or Clinically Impactful Problem.Current gastroenterology reports · 2024Review
- Impedance planimetry during per-oral endoscopic myotomy is associated with decreased inadvertent capnoperitoneum.Surgical endoscopy · 2024Article
- Article
- Current Approach to Dysphagia: A Review Focusing on Esophageal Motility Disorders and Their Treatment.GE Portuguese journal of gastroenterology · 2023Review
- Efficacy of peroral endoscopic myotomy for the treatment of functional esophagogastric junction outflow obstruction.iGIE : innovation, investigation and insights · 2023Article
- What role does the submucosa play in the pathophysiology and treatment of achalasia? An analysis of impedance planimetry during POEM.Surgical endoscopy · 2023Article
- Hypercontractile Esophagus: Clinical and Manometric Features From a Multicenter Korean Cohort.Journal of neurogastroenterology and motility · 2023Article
- Per-oral endoscopic myotomy for the treatment of non-achalasia esophageal dysmotility disorders: experience from a single high-volume center.Surgical endoscopy · 2023Article
- Third-space endoscopy: the final frontier.Gastroenterology report · 2023Review
- Peroral Endoscopic Myotomy for Achalasia.World journal of surgery · 2022Review
- Esophageal Motility Disorders: Current Approach to Diagnostics and Therapeutics.Gastroenterology · 2022Review
Corrections and comments
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Authors and funding
27 authors at 11 institutions in 8 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND STUDY
aimsThe efficacy of per oral endoscopic myotomy (POEM) in non-achalasia esophageal motility disorders such as esophagogastric junction outflow obstruction (EGJOO), diffuse esophageal spasm (DES), and jackhammer esophagus (JE) has not been well demonstrated. The aim of this international multicenter study was to assess clinical outcomes of POEM in patients with non-achalasia disorders, namely DES, JE, and EGJOO, in a large cohort of patients. PATIENTS AND
methodsThis was a retrospective study at 11 centers. Consecutive patients who underwent POEM for EGJOO, DES, or JE between 1/2014 and 9/2016 were included. Rates of technical success (completion of myotomy), clinical response (symptom improvement/Eckardt score ≤ 3), and adverse events (AEs, severity per ASGE lexicon) were ascertained
resultsFifty patients (56 % female; mean age 61.7 years) underwent POEM for EGJOO (n = 15), DES (n = 17), and JE (n = 18). The majority of patients (68 %) were treatment-naïve. Technical success was achieved in all patients with a mean procedural time of 88.4 ± 44.7 min. Mean total myotomy length was 15.1 ± 4.7 cm. Chest pain improved in 88.9 % of EGJOO and 87.0 % of DES/JE (
conclusionPOEM is effective and safe in management of non-achalasia esophageal motility disorders, which include DES, JE, and EGJOO.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.