ArticleBioMed research international2018
Weight Loss in Parkinson's Disease: The Relationship with Motor Symptoms and Disease Progression.
Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- Efficacy and safety of GLP-1 agonists in Parkinson's disease: a systematic review and meta-analysis of randomized controlled trials.Naunyn-Schmiedeberg's archives of pharmacology · 2025Pooled it
- A randomized safety and feasibility crossover trial of two Mediterranean-ketogenic interventions in individuals with Parkinson's disease.Journal of Parkinson's disease · 2026Trial
- Weight changes and physical activity in Parkinson's disease: converging markers of energy balance, disease progression, and lifestyle-based care.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- When the Scale Drops: Pathways to Weight Loss in Parkinson's Disease and Future Directions.Movement disorders : official journal of the Movement Disorder Society · 2026Review
- Exploring the Facilitators and Barriers of Adherence to Mediterranean-Ketogenic Dietary Interventions in Parkinson's Disease: A Qualitative Study.Current developments in nutrition · 2025Article
- Review
- Parkinson's Disease Detection via Bilateral Gait Camera Sensor Fusion Using CMSA-Net and Implementation on Portable Device.Sensors (Basel, Switzerland) · 2025Article
- The profile of gastrointestinal dysfunction in prodromal to late-stage Parkinson's disease.NPJ Parkinson's disease · 2025Article
- U.S. Tax Credits to Promote Practical Proactive Preventative Care for Parkinson's Disease.Journal of Parkinson's disease · 2024Article
- Impact of weight loss for depressive symptom in mid-stage patients with Parkinson's disease: a 4-year follow-up study.Frontiers in neurology · 2023Article
- Oral health-related quality of life in patients with Parkinson's disease.Journal of oral rehabilitation · 2022Article
- Rehabilitation outcomes in Huntington disease patients with low body mass index.Journal of musculoskeletal & neuronal interactions · 2022Article
- Time-dependent alterations in the rat nigrostriatal system after intrastriatal injection of fibrils formed by α-Syn and tau fragments.Frontiers in aging neuroscience · 2022Article
- Odor Identification by Parkinson's Disease Patients Tested by Using Sniffin' Sticks versus Natural Spices.Parkinson's disease · 2022Article
- Constructing Prediction Models for Freezing of Gait by Nomogram and Machine Learning: A Longitudinal Study.Frontiers in neurology · 2021Article
- Characteristic of Parkinson's disease with severe COVID-19: a study of 10 cases from Wuhan.Journal of neural transmission (Vienna, Austria : 1996) · 2021Observational
- Article
- Effect of Olfactory and Gustatory Dysfunction and Motor Symptoms on Body Weight in Patients with Parkinson's Disease.Brain sciences · 2020Article
- Symptom burden among individuals with Parkinson disease: A national survey.Neurology. Clinical practice · 2020Article
- Altered Body Composition and Increased Resting Metabolic Rate Associated with the Postural Instability/Gait Difficulty Parkinson's Disease Subtype.Parkinson's disease · 2020Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo determine the prevalence of weight loss (WL) in PD patients, its relationship to the severity of motor manifestations and appetite changes.
methods144 PD patients and 120 controls were evaluated in a single session. All subjects were asked about changes in body weight and appetite. PD patients were examined with the UPDRS-III and the Hoehn and Yahr (HY) scales. Subscores of tremor, bradykinesia /rigidity, and non-dopaminergic symptoms (NDS) were analyzed individually. Multivariable logistic regression analysis was used to determine an association between WL and PD motor manifestations.
results48.6 % of PD patients presented WL compared to 20.8 % of controls (p < 0.001). Weight losers were significantly older and had longer disease duration, higher scores in HY stages, UPDRS-III, and NDS-subscore. Multivariable logistic regression analysis demonstrated that WL was associated with NDS-subscore (p= 0.002; OR: 1.33) and older age (p= 0.037; OR: 1.05). Appetite in PD cases losing weight was unchanged (35.7 %), decreased (31.4 %), or even increased (32.9).
conclusionsOur results showed that WL occurs in almost half of PD patients and it is largely the consequence of disease progression rather than involuntary movements or a decrease in food intake.
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