Evidence map›Paper›PMID 30105268›Full record

ArticleBioMed research international2018

The Thomsen-Friedenreich Antigen-Specific Antibody Signatures in Patients with Breast Cancer.

Oleg Kurtenkov, Kaire Innos, Boris Sergejev, Kersti Klaamas

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Oleg KurtenkovDepartment of Oncology and Immunology, National Institute for Health Development, Hiiu 42, 11619 Tallinn, Estonia.ORCID 0000-0003-2258-6455
Kaire InnosDepartment of Epidemiology and Biostatistics, National Institute for Health Development, Hiiu 42, 11619 Tallinn, Estonia.
Boris SergejevDepartment of Oncology and Immunology, National Institute for Health Development, Hiiu 42, 11619 Tallinn, Estonia.
Kersti KlaamasDepartment of Oncology and Immunology, National Institute for Health Development, Hiiu 42, 11619 Tallinn, Estonia.ORCID 0000-0002-1129-9031
National Institute for Health Development · EE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alterations in the glycosylation of serum total immunoglobulins show these antibodies to have a diagnostic potential for cancer but the disease-related Abs to the tumor-associated antigens, including glycans, have still poorly been investigated in this respect. We analysed serum samples from patients with breast carcinoma (n = 196) and controls (n = 64) for the level of Thomsen-Friedenreich (TF) antigen-specific antibody isotypes, their sialylation, interrelationships, and the avidity by using ELISA with the synthetic TF-polyacrylamide conjugate as an antigen and the sialic acid-specific

Indexed as

AdultAgedAgglutininsAntigens, Tumor-Associated, CarbohydrateBreast NeoplasmsFemaleHumansMiddle AgedNeoplasm StagingYoung AdultAgglutininsAntigens, Tumor-Associated, CarbohydrateThomsen-Friedenreich antigen

Identifiers

PMID30105268
PMCPMC6076901
OpenAlexW2883712320

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.