Evidence map›Paper›PMID 30105204›Full record

ArticlePhotoacoustics2018

Applying dynamic contrast enhanced MSOT imaging to intratumoral pharmacokinetic modeling.

Ted G Xiao, Jared A Weis, F Scott Gayzik, Alexandra Thomas, Akiko Chiba, Metin N Gurcan, Umit Topaloglu, Abhilash Samykutty, Lacey R McNally

Abstract read
In one paragraph

Article in Photoacoustics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ted G XiaoDepartment of Biomedical Engineering, Wake Forest School of Medicine, Winston-Salem, NC 27101, United States.
Jared A WeisDepartment of Biomedical Engineering, Wake Forest School of Medicine, Winston-Salem, NC 27101, United States.
F Scott GayzikDepartment of Biomedical Engineering, Wake Forest School of Medicine, Winston-Salem, NC 27101, United States.
Alexandra ThomasDepartment of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC 27013, United States.
Akiko ChibaDepartment of Surgery, Wake Forest School of Medicine, Winston-Salem, NC 27013, United States.
Metin N GurcanDepartment of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC 27013, United States.
Umit TopalogluDepartment of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, NC 27013, United States.
Abhilash SamykuttyDepartment of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, NC 27013, United States.
Lacey R McNallyDepartment of Biomedical Engineering, Wake Forest School of Medicine, Winston-Salem, NC 27101, United States.

Funding

Stroma Targeted Theranostic Nanoparticles for Pancreatic CancerR01CA212350 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI MCNALLY, LACEY R · 2017 to 2021
$1.7M
Non-Invasive Detection of Tumor Extracellular pH using Multispectral Optoacoustic TomographyR01CA205941 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI MCNALLY, LACEY R · 2016 to 2021
$1.7M
Theranostic Nanoparticles For Detection and Treatment of Pancreatic CancerR01EB020125 · NIBIB · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI MCNALLY, LACEY R · 2016 to 2019
$1.7M
NCI NIH HHS R01 CA205941NCI NIH HHS R01 CA212350NIBIB NIH HHS R01 EB020125
6 · The paper itself

Abstract

Examining the dynamics of an agent in the tumor microenvironment can offer critical insights to the influx rate and accumulation of the agent. Intratumoral kinetic characterization in the

Indexed as

HypoxiaIntratumoral kineticsMultispectral optoacoustic imagingPharmacokinetic modelingTargeted contrast agentTumor microenvironment

Identifiers

PMID30105204
PMCPMC6086408

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.