Evidence map›Paper›PMID 30105162›Full record

ArticleNeurology. Clinical practice2018

Prevalence of and risk factors for cerebral microbleeds in a general Japanese elderly community.

Tomohiro Yubi, Jun Hata, Tomoyuki Ohara, Naoko Mukai, Yoichiro Hirakawa, Daigo Yoshida, Seiji Gotoh, Naoki Hirabayashi, Yoshihiko Furuta, Tetsuro Ago and 3 more

Abstract read
In one paragraph

Article in Neurology. Clinical practice, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  7. Observational
  8. Review
  9. Article
  10. Associations Between Plasma Ceramides and Cerebral Microbleeds or Lacunes.Arteriosclerosis, thrombosis, and vascular biology · 2020
    Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Tomohiro YubiDepartments of Epidemiology and Public Health (TY, JH, DY, YF, TN), Department of Neuropsychiatry (TO), Center for Cohort Studies (NM), Department of Medicine and Clinical Sciences (YH, SG, TA, TK), and Department of Psychosomatic Medicine (NH), Graduate School of Medical Sciences, Kyushu University, Fukuoka; and Hisayama Research Institute for Lifestyle Diseases (YK), Fukuoka, Japan.
Jun HataDepartments of Epidemiology and Public Health (TY, JH, DY, YF, TN), Department of Neuropsychiatry (TO), Center for Cohort Studies (NM), Department of Medicine and Clinical Sciences (YH, SG, TA, TK), and Department of Psychosomatic Medicine (NH), Graduate School of Medical Sciences, Kyushu University, Fukuoka; and Hisayama Research Institute for Lifestyle Diseases (YK), Fukuoka, Japan.
Tomoyuki OharaDepartments of Epidemiology and Public Health (TY, JH, DY, YF, TN), Department of Neuropsychiatry (TO), Center for Cohort Studies (NM), Department of Medicine and Clinical Sciences (YH, SG, TA, TK), and Department of Psychosomatic Medicine (NH), Graduate School of Medical Sciences, Kyushu University, Fukuoka; and Hisayama Research Institute for Lifestyle Diseases (YK), Fukuoka, Japan.
Naoko MukaiDepartments of Epidemiology and Public Health (TY, JH, DY, YF, TN), Department of Neuropsychiatry (TO), Center for Cohort Studies (NM), Department of Medicine and Clinical Sciences (YH, SG, TA, TK), and Department of Psychosomatic Medicine (NH), Graduate School of Medical Sciences, Kyushu University, Fukuoka; and Hisayama Research Institute for Lifestyle Diseases (YK), Fukuoka, Japan.
Yoichiro HirakawaDepartments of Epidemiology and Public Health (TY, JH, DY, YF, TN), Department of Neuropsychiatry (TO), Center for Cohort Studies (NM), Department of Medicine and Clinical Sciences (YH, SG, TA, TK), and Department of Psychosomatic Medicine (NH), Graduate School of Medical Sciences, Kyushu University, Fukuoka; and Hisayama Research Institute for Lifestyle Diseases (YK), Fukuoka, Japan.
Daigo YoshidaDepartments of Epidemiology and Public Health (TY, JH, DY, YF, TN), Department of Neuropsychiatry (TO), Center for Cohort Studies (NM), Department of Medicine and Clinical Sciences (YH, SG, TA, TK), and Department of Psychosomatic Medicine (NH), Graduate School of Medical Sciences, Kyushu University, Fukuoka; and Hisayama Research Institute for Lifestyle Diseases (YK), Fukuoka, Japan.
Seiji GotohDepartments of Epidemiology and Public Health (TY, JH, DY, YF, TN), Department of Neuropsychiatry (TO), Center for Cohort Studies (NM), Department of Medicine and Clinical Sciences (YH, SG, TA, TK), and Department of Psychosomatic Medicine (NH), Graduate School of Medical Sciences, Kyushu University, Fukuoka; and Hisayama Research Institute for Lifestyle Diseases (YK), Fukuoka, Japan.
Naoki HirabayashiDepartments of Epidemiology and Public Health (TY, JH, DY, YF, TN), Department of Neuropsychiatry (TO), Center for Cohort Studies (NM), Department of Medicine and Clinical Sciences (YH, SG, TA, TK), and Department of Psychosomatic Medicine (NH), Graduate School of Medical Sciences, Kyushu University, Fukuoka; and Hisayama Research Institute for Lifestyle Diseases (YK), Fukuoka, Japan.
Yoshihiko FurutaDepartments of Epidemiology and Public Health (TY, JH, DY, YF, TN), Department of Neuropsychiatry (TO), Center for Cohort Studies (NM), Department of Medicine and Clinical Sciences (YH, SG, TA, TK), and Department of Psychosomatic Medicine (NH), Graduate School of Medical Sciences, Kyushu University, Fukuoka; and Hisayama Research Institute for Lifestyle Diseases (YK), Fukuoka, Japan.
Tetsuro AgoDepartments of Epidemiology and Public Health (TY, JH, DY, YF, TN), Department of Neuropsychiatry (TO), Center for Cohort Studies (NM), Department of Medicine and Clinical Sciences (YH, SG, TA, TK), and Department of Psychosomatic Medicine (NH), Graduate School of Medical Sciences, Kyushu University, Fukuoka; and Hisayama Research Institute for Lifestyle Diseases (YK), Fukuoka, Japan.
Takanari KitazonoDepartments of Epidemiology and Public Health (TY, JH, DY, YF, TN), Department of Neuropsychiatry (TO), Center for Cohort Studies (NM), Department of Medicine and Clinical Sciences (YH, SG, TA, TK), and Department of Psychosomatic Medicine (NH), Graduate School of Medical Sciences, Kyushu University, Fukuoka; and Hisayama Research Institute for Lifestyle Diseases (YK), Fukuoka, Japan.
Yutaka KiyoharaDepartments of Epidemiology and Public Health (TY, JH, DY, YF, TN), Department of Neuropsychiatry (TO), Center for Cohort Studies (NM), Department of Medicine and Clinical Sciences (YH, SG, TA, TK), and Department of Psychosomatic Medicine (NH), Graduate School of Medical Sciences, Kyushu University, Fukuoka; and Hisayama Research Institute for Lifestyle Diseases (YK), Fukuoka, Japan.
Toshiharu NinomiyaDepartments of Epidemiology and Public Health (TY, JH, DY, YF, TN), Department of Neuropsychiatry (TO), Center for Cohort Studies (NM), Department of Medicine and Clinical Sciences (YH, SG, TA, TK), and Department of Psychosomatic Medicine (NH), Graduate School of Medical Sciences, Kyushu University, Fukuoka; and Hisayama Research Institute for Lifestyle Diseases (YK), Fukuoka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe investigated the prevalence of and risk factors for cerebral microbleeds (CMBs) in a cross-sectional study of a general population of Japanese elderly.

methodsIn 2012, brain MRI scanning at 1.5T and comprehensive health examination were conducted for 1281 residents aged 65 years or older. CMBs were defined as ovoid hypointensity lesions less than 10 mm in diameter on T2*-weighted images and classified into deep/infratentorial or lobar CMBs. Age- and sex-specific and overall prevalence of CMBs were estimated, and the associations of traditional cardiovascular risk factors and

resultsThe crude prevalences of total, deep/infratentorial, and lobar CMBs were 18.7% (n = 240), 13.5% (n = 173), and 9.6% (n = 123), respectively. The prevalence of total CMBs was 23.0% in men and 15.5% in women and increased with aging in both sexes (both

conclusionsOur study suggests that approximately 1 of 5 Japanese elderly people have CMBs, and that risk factors for deep/infratentorial and lobar CMBs are different, indicating the distinct pathologic backgrounds of these lesions.

Identifiers

PMID30105162
PMCPMC6075994

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