ArticleNeuropsychiatric disease and treatment2018
Cytological and cytometric analysis of oral mucosa in patients with Alzheimer's and Parkinson's disease.
Article in Neuropsychiatric disease and treatment, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 9 citations in OpenAlex.
- Genome-Scale Expression Pattern of Long Non-Coding RNAs in Chinese Uyghur Patients with Parkinson's Disease.Medical science monitor : international medical journal of experimental and clinical research · 2020Trial
- Non-Oral Drug Delivery in Parkinson's Disease: Current Applications and Future.Turkish journal of pharmaceutical sciences · 2022Article
- Oral Mucosa Derived α-Synuclein as a Potential Diagnostic Biomarker for Parkinson's Disease.Frontiers in aging neuroscience · 2022Article
- Diagnostic Biomarkers for Alzheimer's Disease Using Non-Invasive Specimens.Journal of clinical medicine · 2020Review
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Authors and funding
5 authors at 3 institutions in 1 country.
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Abstract
backgroundAlzheimer's disease (AD) and Parkinson's disease (PD) are the two most common neurodegenerative diseases. Recent studies have sought to identify precursor symptoms of AD and PD that occur before the onset of the disease. We evaluated changes in the oral mucosa of patients with AD and PD using a stereological method. PATIENTS AND
methodsThe study included 29 patients with AD, 30 patients with idiopathic PD, and 30 healthy volunteers. Brush biopsies were obtained from all participants, and the nucleator method was used to estimate the volume of cells obtained from the buccal mucosa.
resultsCytomorphometric analysis revealed that the nuclear volume was 484.39±117.10 µm
conclusionThe cytomorphometric analysis revealed no significant differences in the cytoplasmic and nuclear volumes of buccal cells obtained from patients with AD and PD and healthy volunteers.
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