Evidence map›Paper›PMID 30104874›Full record

ArticleInternational journal of nanomedicine2018

The effect of the carbodiimide cross-linker on the structural and biocompatibility properties of collagen-chondroitin sulfate electrospun mat.

Sheyda Akhshabi, Esmaeil Biazar, Vivek Singh, Saeed Heidari Keshel, Nagaraja Geetha

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Review
  3. Chemical Crosslinking of Acid Soluble Collagen Fibres.Biomimetics (Basel, Switzerland) · 2025
    Review
  4. Article
  5. Review
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  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Electrospun Aligned Coaxial Nanofibrous Scaffold for Cardiac Repair.Methods in molecular biology (Clifton, N.J.) · 2021
    Article
  14. Article
  15. Article
  16. Nanotechnology in regenerative ophthalmology.Advanced drug delivery reviews · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Sheyda AkhshabiDepartment of Studies in Biotechnology, University of Mysore, Manasagangotri, Mysuru, Karnataka, India, geetha@appbot.uni-mysore.ac.in.
Esmaeil BiazarDepartment of Biomaterials Engineering, Tonekabon Branch, Islamic Azad University, Tonekabon, Iran.
Vivek SinghProf Brien Holden Eye Research Center, Sudhakar and Sreekanth Ravi Stem Cell Biology Laboratory, L. V. Prasad Eye Institute, Hyderabad, Telangana, India.
Saeed Heidari KeshelDepartment of Tissue Engineering and Applied Cell Sciences, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Nagaraja GeethaDepartment of Studies in Biotechnology, University of Mysore, Manasagangotri, Mysuru, Karnataka, India, geetha@appbot.uni-mysore.ac.in.
University of Mysore · INIslamic Azad University Tonekabon · IRL V Prasad Eye Institute · INShahid Beheshti University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCollagen and chondroitin sulfate (CS) are an essential component of the natural extracellular matrix (ECM) of most tissues. They provide the mechanical stability to cone the compressive forces in ECM. In tissue engineering, electrospun nanofibrous scaffolds prepared by electrospinning technique have emerged as a suitable candidate to imitate natural ECM functions. Cross-linking with 1-ethyl-3-(3-dimethyl-aminopropyl)-1-carbodiimide hydrochloride/ MATERIALS AND

methodsThis study has synthesized nanofibrous collagen-CS scaffolds by using the electrospinning method.

resultsThe results have shown that incorporation of CS in higher concentration, along with 1-ethyl-3-(3-dimethyl-aminopropyl)-1-carbodiimide hydrochloride/

conclusionThese results demonstrate that cross-linked electrospun CO-CS mats exhibited a uniform nanofibrous and porous structure, especially for lower concentration of the cross-linker and may be utilized as an alternative effective substrate in tissue engineering.

Indexed as

AnimalsBiocompatible MaterialsCarbodiimidesChondroitin SulfatesCollagenCross-Linking ReagentsEpithelial CellsEpithelium, CornealExtracellular MatrixFishesHumansNanofibersPorositySharksSpectroscopy, Fourier Transform InfraredTissue EngineeringBiocompatible MaterialsCarbodiimidesChondroitin SulfatesCollagenCross-Linking Reagentschondroitin sulfatecollagencross linkerCSECMelectrospinningextracellular matrixnanofiber

Identifiers

PMID30104874
PMCPMC6071624
OpenAlexW2885462958

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.