Evidence map›Paper›PMID 30104793›Full record

ArticleBulletin of the World Health Organization2018

Hypertensive disorders in pregnancy and stillbirth rates: a facility-based study in China.

Tao Xiong, Yi Mu, Juan Liang, Jun Zhu, Xiaohong Li, Jinke Li, Zheng Liu, Yi Qu, Yanping Wang, Dezhi Mu

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bulletin of the World Health Organization, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 4 pooled it
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 4 syntheses or guidelines pooled it, 98 citations in OpenAlex.

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  13. Adherence to recommended prenatal visit schedules and risk for stillbirth, according to probable cause of death.European journal of obstetrics, gynecology, and reproductive biology · 2024
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  14. Epidemiology and placental pathology of intrauterine fetal demise in a tertiary hospital in the Philippines.European journal of obstetrics & gynecology and reproductive biology: X · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Tao XiongDepartment of Paediatrics, Key Laboratory of Birth Defects and Related Diseases of Women and Children of the Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Yi MuNational Office for Maternal and Child Health Surveillance Sichuan University, Chengdu, China.
Juan LiangNational Office for Maternal and Child Health Surveillance Sichuan University, Chengdu, China.
Jun ZhuNational Office for Maternal and Child Health Surveillance Sichuan University, Chengdu, China.
Xiaohong LiNational Office for Maternal and Child Health Surveillance Sichuan University, Chengdu, China.
Jinke LiNational Office for Maternal and Child Health Surveillance Sichuan University, Chengdu, China.
Zheng LiuNational Office for Maternal and Child Health Surveillance Sichuan University, Chengdu, China.
Yi QuDepartment of Paediatrics, Key Laboratory of Birth Defects and Related Diseases of Women and Children of the Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Yanping WangNational Office for Maternal and Child Health Surveillance Sichuan University, Chengdu, China.
Dezhi MuDepartment of Paediatrics, Key Laboratory of Birth Defects and Related Diseases of Women and Children of the Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Maternal and Child Health Hospital of Sichuan Province · CNSichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the association between hypertensive disorders in pregnancy and the stillbirth rate.

methodsWe obtained all data from China's National Maternal Near Miss Surveillance System for 2012 to 2016. Associations between hypertensive disorders in pregnancy and stillbirths, stratified by fetus number and gestational age, were assessed using Poisson regression analysis with a robust variance estimator.

findingsFor the period, 6 970 032 births, including 66 494 stillbirths, were reported to the surveillance system. The weighted stillbirth rate in women with a hypertensive disorder in pregnancy was 21.9 per 1000 births. The risk was higher in those who had received few antenatal care visits or who were poorly educated. For singleton pregnancies, the adjusted risk ratio (aRR) for a stillbirth among women with hypertensive disorders in pregnancy compared with normotensive women was 3.1 (95% confidence interval, CI: 2.85-3.37). The aRR for hypertensive disorder subtypes was: 6.66 (95% CI: 5.57-7.96) for superimposed preeclampsia; 4.15 (95% CI: 3.81-4.52) for preeclampsia or eclampsia; 2.32 (95% CI: 1.87-2.88) for chronic hypertension; and 1.21 (95% CI: 1.08-1.36) for gestational hypertension. For multiple pregnancies, the association between stillbirths and hypertensive disorders in pregnancy was not significant, except for superimposed preeclampsia (aRR: 1.95; 95% CI: 1.28-2.97).

conclusionTo minimize the incidence of stillbirths, more attention should be paid to chronic hypertension and superimposed preeclampsia in singleton pregnancies and to superimposed preeclampsia in multiple pregnancies. Better quality antenatal care and improved guidelines are needed in China.

Indexed as

Cesarean SectionChinaFemaleHumansHypertensionHypertension, Pregnancy-InducedMalePre-EclampsiaPregnancyPregnancy OutcomeStillbirth

Identifiers

PMID30104793
PMCPMC6083384
OpenAlexW2885001224

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.