Evidence map›Paper›PMID 30104792›Full record

ArticleBulletin of the World Health Organization2018

Patient-led active tuberculosis case-finding in the Democratic Republic of the Congo.

Emmanuel André, Olivier Rusumba, Carlton A Evans, Philippe Ngongo, Pasteur Sanduku, Marhegane Munguakonkwa Elvis, Habimana Ndwanyi Celestin, Ishara Rusumba Alain, Eric Mulume Musafiri, Jean-Pierre Kabuayi and 4 more

Abstract read
In one paragraph

Article in Bulletin of the World Health Organization, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Emmanuel AndréDepartment of Microbiology and Immunology, KU Leuven, Herestraat 49, Box 1030, 3000 Leuven, Belgium.
Olivier RusumbaAmbassadeurs de Lutte Contre la Tuberculose, Bukavu, Democratic Republic of Congo.
Carlton A EvansSection of Infectious Diseases and Immunity, Imperial College London, London, England.
Philippe NgongoCoordination Provinciale Lèpre et Tuberculose du Sud-Kivu, Bukavu, Democratic Republic of Congo.
Pasteur SandukuCoordination Provinciale Lèpre et Tuberculose du Sud-Kivu, Bukavu, Democratic Republic of Congo.
Marhegane Munguakonkwa ElvisAmbassadeurs de Lutte Contre la Tuberculose, Bukavu, Democratic Republic of Congo.
Habimana Ndwanyi CelestinAmbassadeurs de Lutte Contre la Tuberculose, Bukavu, Democratic Republic of Congo.
Ishara Rusumba AlainAmbassadeurs de Lutte Contre la Tuberculose, Bukavu, Democratic Republic of Congo.
Eric Mulume MusafiriCoordination Provinciale Lèpre et Tuberculose du Sud-Kivu, Bukavu, Democratic Republic of Congo.
Jean-Pierre KabuayiChallenge TB, United States Agency for International Development, United States of America.
Olivier le Polain de WarouxDepartment of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, England.
Nadia Aït-KhaledInternational Union against Tuberculosis and Lung Disease, Paris, France.
Michel DelméeInstitut de Recherche Expérimentale et Clinique, Université Catholique de Louvain, Brussels, Belgium.
Francis ZechInstitut de Recherche Expérimentale et Clinique, Université Catholique de Louvain, Brussels, Belgium.

Funding

Medical Research Council MR/K007467/1Wellcome Trust 201251/Z/16/Z
6 · The paper itself

Abstract

objectiveTo investigate the effect of using volunteer screeners in active tuberculosis case-finding in South Kivu, the Democratic Republic of the Congo, especially among groups at high risk of tuberculosis infection.

methodsTo identify and screen high-risk groups in remote communities, we trained volunteer screeners, mainly those who had themselves received treatment for tuberculosis or had a family history of the disease. A non-profit organization was created and screeners received training on the disease and its transmission at 3-day workshops. Screeners recorded the number of people screened, reporting a prolonged cough and who attended a clinic for testing, as well as test results. Data were evaluated every quarter during the 3-year period of the intervention (2014-2016).

findingsAcceptability of the intervention was high. Volunteers screened 650 434 individuals in their communities, 73 418 of whom reported a prolonged cough; 50 368 subsequently attended a clinic for tuberculosis testing. Tuberculosis was diagnosed in 1 in 151 people screened, costing 0.29 United States dollars (US$) per person screened and US$ 44 per person diagnosed. Although members of high-risk groups with poorer access to health care represented only 5.1% (33 002/650 434) of those screened, they contributed 19.7% (845/4300) of tuberculosis diagnoses (1 diagnosis per 39 screened). The intervention resulted in an additional 4300 sputum-smear-positive pulmonary tuberculosis diagnoses, 42% (4 300/10 247) of the provincial total for that period.

conclusionPatient-led active tuberculosis case-finding represents a valuable complement to traditional case-finding, and should be used to assist health systems in the elimination of tuberculosis.

Indexed as

VolunteersAntitubercular AgentsCommunity Health ServicesDemocratic Republic of the CongoFemaleHumansMaleMass ScreeningPoverty AreasRural PopulationSputumTuberculosis, PulmonaryAntitubercular Agents

Identifiers

PMID30104792
PMCPMC6083386

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.