Evidence map›Paper›PMID 30104744›Full record

ReviewNature reviews. Neurology2018

The complex aetiology of cerebral palsy.

Steven J Korzeniewski, Jaime Slaughter, Madeleine Lenski, Peterson Haak, Nigel Paneth

Erratum issued Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT05134259 (The Role of Repetitive Transcranial Magnetic Stimulation in Spastic Hemiplegic Cerebral Palsy in a Sample of Egyptian Children), which is not on this map. Cited by 100 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
100citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05134259 naunknown statusnot on this mapstarted 2022, after this paper: background citation

The Role of Repetitive Transcranial Magnetic Stimulation in Spastic Hemiplegic Cerebral Palsy in a Sample of Egyptian Children

TypeinterventionalSponsorAl-Azhar UniversityRan2022 to 2022Enrolled60ConditionsCerebral PalsyArmsRepetitive Transcranial Magnetic Stimulation
3 · Its place in the literature

Who cites it

100 citing papers in PubMed, 9 syntheses or guidelines pooled it.

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  4. Systematic review and network meta-analysis of robot-assisted gait training on lower limb function in patients with cerebral palsy.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023
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40 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Steven J KorzeniewskiDepartment of Obstetrics & Gynecology, Wayne State University School of Medicine, Detroit, MI, USA. sKorzeni@med.wayne.edu.
Jaime SlaughterDepartment of Health Systems and Sciences Research and Department of Epidemiology and Biostatistics, Drexel University, Philadelphia, PA, USA.
Madeleine LenskiDepartment of Epidemiology and Biostatistics, College of Human Medicine, Michigan State University, East Lansing, MI, USA.
Peterson HaakMichigan Department of Health and Human Services, Lansing, MI, USA.
Nigel PanethDepartment of Epidemiology and Biostatistics, College of Human Medicine, Michigan State University, East Lansing, MI, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cerebral palsy (CP) is the most prevalent, severe and costly motor disability of childhood. Consequently, CP is a public health priority for prevention, but its aetiology has proved complex. In this Review, we summarize the evidence for a decline in the birth prevalence of CP in some high-income nations, describe the epidemiological evidence for risk factors, such as preterm delivery and fetal growth restriction, genetics, pregnancy infection and other exposures, and discuss the success achieved so far in prevention through the use of magnesium sulfate in preterm labour and therapeutic hypothermia for birth-asphyxiated infants. We also consider the complexities of disentangling prenatal and perinatal influences, and of establishing subtypes of the disorder, with a view to accelerating the translation of evidence into the development of strategies for the prevention of CP.

Indexed as

Cerebral PalsyCongenital AbnormalitiesGenetic Predisposition to DiseaseInfant, Premature, DiseasesPregnancy ComplicationsAnticonvulsantsChildFemaleHumansHypothermia, InducedInfant, NewbornMagnesium SulfatePregnancyAnticonvulsantsMagnesium Sulfate

Identifiers

PMID30104744

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.