Evidence map›Paper›PMID 30104658›Full record

ArticleTranslational psychiatry2018

Bipolar mood cycles associated with lunar entrainment of a circadian rhythm.

Thomas A Wehr

Open access · goldAbstract read
In one paragraph

Article in Translational psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. Lunar gravity predicts sleep timing.bioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Epileptiform Activity and Seizure Risk Follow Long-Term Non-Linear Attractor Dynamics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Thomas A WehrIntramural Research Program, National Institute of Mental Health, Bethesda, MD, USA. wehr.tom@gmail.com.
National Institute of Mental Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In bipolar disorder, episodes of depression and mania are associated with dramatic disturbances in sleep, which experiments show are likely to contribute to the pathogenesis of the episodes. A recent finding that 18 patients' manic-depressive cycles oscillated in synchrony with biweekly surges in amplitude of the moon's tides provided a clue to the cause of the sleep-disturbances. Analyses of one of the patients' sleep-wake cycles suggest that his mood cycles arose when a circadian rhythm that normally is entrained to dawn and controls the daily onset of wakefulness became entrained instead to 24.8-h recurrences of every second 12.4-h tidal cycle. The finding provides the basis for a comprehensive description of the pathogenesis and pathophysiology of the mood cycle.

Indexed as

MoonAffectBipolar DisorderCircadian RhythmHumansMaleMiddle AgedSleepSleep Wake DisordersWakefulness

Identifiers

PMID30104658
PMCPMC6089884
OpenAlexW2885275531

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.