Evidence map›Paper›PMID 30104406›Full record

ArticleThe EMBO journal2018

The PEAT protein complexes are required for histone deacetylation and heterochromatin silencing.

Lian-Mei Tan, Cui-Jun Zhang, Xiao-Mei Hou, Chang-Rong Shao, Yu-Jia Lu, Jin-Xing Zhou, Yong-Qiang Li, Lin Li, She Chen, Xin-Jian He

Open access · bronzeAbstract read
In one paragraph

Article in The EMBO journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 97 citations in OpenAlex.

  1. Pooled it
  2. Proceedings of the National Academy of Sciences of the United States of America · 2026
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  9. The leaves fall, yet the tree endures.Cellular and molecular life sciences : CMLS · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Lian-Mei TanNational Institute of Biological Sciences, Beijing, China.
Cui-Jun ZhangNational Institute of Biological Sciences, Beijing, China.ORCID 0000-0002-3286-6912
Xiao-Mei HouNational Institute of Biological Sciences, Beijing, China.
Chang-Rong ShaoNational Institute of Biological Sciences, Beijing, China.
Yu-Jia LuNational Institute of Biological Sciences, Beijing, China.
Jin-Xing ZhouNational Institute of Biological Sciences, Beijing, China.
Yong-Qiang LiNational Institute of Biological Sciences, Beijing, China.
Lin LiNational Institute of Biological Sciences, Beijing, China.
She ChenNational Institute of Biological Sciences, Beijing, China.
Xin-Jian HeNational Institute of Biological Sciences, Beijing, China hexinjian@nibs.ac.cn.ORCID 0000-0002-2878-7461
National Institute of Biological Sciences, Beijing · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In eukaryotes, heterochromatin regions are typically subjected to transcriptional silencing. DNA methylation has an important role in such silencing and has been studied extensively. However, little is known about how methylated heterochromatin regions are subjected to silencing. We conducted a genetic screen and identified an

Indexed as

AcetylationArabidopsisArabidopsis ProteinsGene Expression Regulation, PlantGene SilencingHeterochromatinHistonesMultiprotein ComplexesArabidopsis ProteinsHeterochromatinHistonesMultiprotein ComplexesDNA methylationEPLheterochromatin silencinghistone deacetylationPEAT complexsiRNA

Identifiers

PMID30104406
PMCPMC6166130
OpenAlexW2885781795

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.