Evidence map›Paper›PMID 30104361›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Silkworm genetic sexing through W chromosome-linked, targeted gene integration.

Zhongjie Zhang, Baolong Niu, Dongfeng Ji, Muwang Li, Kai Li, Anthony A James, Anjiang Tan, Yongping Huang

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
  2. Emerging tools to advance neuroethology in butterflies and moths.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Engineering a complex, multiple enzyme-mediated synthesis of natural plant pigments in the silkworm,Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Natural and Engineered Sex Ratio Distortion in Insects.Frontiers in ecology and evolution · 2022
    Article
  14. CRISPR/Cas9-mediatedFrontiers in physiology · 2022
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Zhongjie ZhangKey Laboratory of Insect Developmental and Evolutionary Biology, Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, 200032 Shanghai, China.
Baolong NiuSericultural Research Institute, Zhejiang Academy of Agricultural Sciences, 310021 Hangzhou, China.
Dongfeng JiSericultural Research Institute, Zhejiang Academy of Agricultural Sciences, 310021 Hangzhou, China.
Muwang LiSericultural Research Institute, Jiangsu University of Science and Technology, 212018 Zhenjiang, China.
Kai LiSchool of Life Science, East China Normal University, 200062 Shanghai, China.
Anthony A JamesDepartment of Microbiology & Molecular Genetics, University of California, Irvine, CA 92697-3900; aajames@uci.edu ajtan01@sibs.ac.cn yphuang@sibs.ac.cn.
Anjiang TanKey Laboratory of Insect Developmental and Evolutionary Biology, Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, 200032 Shanghai, China; aajames@uci.edu ajtan01@sibs.ac.cn yphuang@sibs.ac.cn.
Yongping HuangKey Laboratory of Insect Developmental and Evolutionary Biology, Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, 200032 Shanghai, China; aajames@uci.edu ajtan01@sibs.ac.cn yphuang@sibs.ac.cn.
Sericultural Research Institute · CNChinese Academy of Sciences · CNCenter for Excellence in Molecular Plant Sciences · CNEast China Normal University · CNUniversity of California, Irvine · US

Funding

Investigation of metabolites related to manganese exposureF31ES027304 · NIEHS · UNIVERSITY OF WASHINGTON · PI BAKER, MARISSA GAYL · 2016 to 2017
$61k
NIEHS NIH HHS 27304C2054
6 · The paper itself

Abstract

Sex separation methods are critical for genetic sexing systems in commercial insect production and sterile insect techniques. Integration of selectable marker genes into a sex chromosome is particularly useful in insects with a heterogametic sex determination system. Here, we describe targeted gene integration of fluorescent marker expression cassettes into a randomly amplified polymorphic DNA (RAPD) marker region in the W chromosome of the lepidopteran model insect

Indexed as

CRISPR-Cas SystemsSex Determination ProcessesAnimalsBombyxChromosomes, InsectFemaleGene EditingMaleSex Chromosomesfemale lethalityLepidopteratransgenesisW chromosome

Identifiers

PMID30104361
PMCPMC6126770
OpenAlexW2886855170

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.