ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2018
Posterior Parietal Cortex Dysfunction Is Central to Working Memory Storage and Broad Cognitive Deficits in Schizophrenia.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 92 citations in OpenAlex.
- Anodal tDCS over right DLPFC does not improve visuospatial working memory in schizophrenia: a single-session, sham-controlled study.BMC psychiatry · 2026Trial
- Transcranial direct current stimulation and cognitive training in the treatment of cognitive deficit in schizophrenia: a randomized controlled trial.BMC psychiatry · 2026Trial
- Effect of transcranial direct current stimulation with concurrent cognitive performance targeting posterior parietal cortex vs prefrontal cortex on working memory in schizophrenia: a randomized clinical trial.Translational psychiatry · 2024Trial
- Intermittent theta burst stimulation over the parietal cortex has a significant neural effect on working memory.Human brain mapping · 2022Trial
- ΔNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2020Trial
- Shared Genetic Networks in Schizophrenia and Bipolar Disorder: Hippocampal Volume-Mediated Neurobiological Mechanisms.Schizophrenia bulletin · 2026Article
- Altered Brain Structure in an ATRX-Deficient Mouse Model of Autism Spectrum Disorder.Autism research : official journal of the International Society for Autism Research · 2026Article
- Peripheral NMDAR subunits as predictors of working memory improvement in schizophrenia.Schizophrenia (Heidelberg, Germany) · 2025Article
- Brain functional connectivity associated with cognitive deficits in younger patients at first episode of schizophrenia.Schizophrenia research. Cognition · 2025Article
- Reduced temporal variability of cortical excitation/inhibition ratio in schizophrenia.Schizophrenia (Heidelberg, Germany) · 2025Article
- Abnormalities in attention and working memory in schizophrenia: The hyperfocusing hypothesis.Current directions in psychological science · 2025Article
- Network integration and segregation changes in schizophrenia: impact of electroconvulsive therapy.BMC psychiatry · 2024Article
- Enhancing visual working memory in schizophrenia: effects of frontoparietal theta tACS in low-performing patients.Schizophrenia (Heidelberg, Germany) · 2024Article
- Article
- External cues improve visual working memory encoding in the presence of salient distractors in schizophrenia.Psychological medicine · 2024Article
- Effects of electroconvulsive therapy on functional brain networks in patients with schizophrenia.BMC psychiatry · 2024Article
- Graph neural network and machine learning analysis of functional neuroimaging for understanding schizophrenia.BMC neuroscience · 2024Article
- Divergent pattern of functional connectivity within the dorsal attention network differentiates schizophrenia and bipolar disorder patients.Frontiers in psychiatry · 2024Article
- Striatum-projecting prefrontal cortex neurons support working memory maintenance.Nature communications · 2023Article
- Value of P300 amplitude in the diagnosis of untreated first-episode schizophrenia and psychosis risk syndrome in children and adolescents.BMC psychiatry · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
PFC dysfunction is widely believed to underlie working memory (WM) deficits in people with schizophrenia (PSZ), but few studies have focused on measures of WM storage devoid of manipulation. Research in neurotypical individuals has shown that storage capacity is more closely related to posterior parietal cortex (PPC) than PFC, suggesting that reductions in WM storage capacity in schizophrenia that are associated with broad cognitive deficits may be related to neural activity in PPC. In the present human neuroimaging study, 37 PSZ and 37 matched healthy control subjects of either sex completed a change detection task with varying set sizes while undergoing fMRI. The task was designed to emphasize WM storage with minimal top-down control demands. Whole-brain analysis identified areas in which BOLD activity covaried with the number of items maintained in WM (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.