Evidence map›Paper›PMID 30104328›Full record

SynthesisThe British journal of general practice : the journal of the Royal College of General Practitioners2018

Direct access cancer testing in primary care: a systematic review of use and clinical outcomes.

Claire Friedemann Smith, Alice C Tompson, Nicholas Jones, Josh Brewin, Elizabeth A Spencer, Clare R Bankhead, Fd Richard Hobbs, Brian D Nicholson

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in The British journal of general practice : the journal of the Royal College of General Practitioners, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Direct access cancer testing in primary care: a systematic review of use and clinical outcomes.The British journal of general practice : the journal of the Royal College of General Practitioners · 2018
    Pooled it
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Community diagnostic centres: bringing diagnostics closer to home.The British journal of general practice : the journal of the Royal College of General Practitioners · 2021
    Article
  9. Article
  10. Article
  11. Article
  12. Patient experiences of the urgent cancer referral pathway-Can the NHS do better? Semi-structured interviews with patients with upper gastrointestinal cancer.Health expectations : an international journal of public participation in health care and health policy · 2020
    Article
  13. Negotiating the risks of computed tomography in primary care.The British journal of general practice : the journal of the Royal College of General Practitioners · 2020
    Review
  14. The elusive diagnosis of cancer: testing times.The British journal of general practice : the journal of the Royal College of General Practitioners · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Claire Friedemann SmithNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford.
Alice C TompsonNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford.
Nicholas JonesNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford.
Josh BrewinNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford.
Elizabeth A SpencerNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford.
Clare R BankheadNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford.
Fd Richard HobbsNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford.
Brian D NicholsonNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford.
University of Oxford · GB

Funding

Cancer Research UK 19383Department of Health IS-SPC-0514-10043
6 · The paper itself

Abstract

backgroundDirect access (DA) testing allows GPs to refer patients for investigation without consulting a specialist. The aim is to reduce waiting time for investigations and unnecessary appointments, enabling treatment to begin without delay.

aimTo establish the proportion of patients diagnosed with cancer and other diseases through DA testing, time to diagnosis, and suitability of DA investigations. DESIGN AND

settingSystematic review assessing the effectiveness of GP DA testing in adults.

methodMEDLINE, Embase, and the Cochrane Library were searched. Where possible, study data were pooled and analysed quantitatively. Where this was not possible, the data are presented narratively.

resultsThe authors identified 60 papers that met pre-specified inclusion criteria. Most studies were carried out in the UK and were judged to be of poor quality. The authors found no significant difference in the pooled cancer conversion rate between GP DA referrals and patients who first consulted a specialist for any test, except gastroscopy. There were also no significant differences in the proportions of patients receiving any non-cancer diagnosis. Referrals for testing were deemed appropriate in 66.4% of those coming from GPs, and in 80.9% of those from consultants; this difference was not significant. The time from referral to testing was significantly shorter for patients referred for DA tests. Patient and GP satisfaction with DA testing was consistently high.

conclusionGP DA testing performs as well as, and on some measures better than, consultant triaged testing on measures of disease detection, appropriateness of referrals, interval from referral to testing, and patient and GP satisfaction.

Indexed as

Early Detection of CancerPrimary Health CareHumansNeoplasmsOutcome Assessment, Health CareReferral and ConsultationTime-to-Treatmentcancerdiagnosisdiagnostic testshealth services accessibility/standardsprimary care

Identifiers

PMID30104328
PMCPMC6104856
OpenAlexW2887109683

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.