Evidence map›Paper›PMID 30104269›Full record

ArticleAntimicrobial agents and chemotherapy2018

Screening a Repurposing Library for Inhibitors of Multidrug-Resistant Candida auris Identifies Ebselen as a Repositionable Candidate for Antifungal Drug Development.

Gina Wall, Ashok K Chaturvedi, Floyd L Wormley, Nathan P Wiederhold, Hoja P Patterson, Thomas F Patterson, José L Lopez-Ribot

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
6.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 88 citations in OpenAlex.

  1. Pharmacological advances inJournal of enzyme inhibition and medicinal chemistry · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Antifungal therapy ofBiofilm · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Evaluation of the synergistic antifungal activity of micafungin and voriconazole plus sertraline against Candida auris.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022
    Article
  16. Review
  17. Article
  18. Article
  19. Flavonoid-Rich Fractions ofPlants (Basel, Switzerland) · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Gina WallDepartment of Biology, South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, Texas, USA.
Ashok K ChaturvediDepartment of Biology, South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, Texas, USA.
Floyd L WormleyDepartment of Biology, South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, Texas, USA.
Nathan P WiederholdDepartment of Pathology and Laboratory Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.ORCID 0000-0002-2225-5122
Hoja P PattersonDepartment of Pathology and Laboratory Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Thomas F PattersonDepartment of Medicine, Division of Infectious Diseases, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
José L Lopez-RibotDepartment of Biology, South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, Texas, USA jose.lopezribot@utsa.edu.
Texas Center for Infectious Disease · USThe University of Texas Health Science Center at San Antonio · US

Funding

UTSA RISE Research Training ProgramR25GM060655 · NIGMS · UNIVERSITY OF TEXAS SAN ANTONIO · PI BAREA-RODRIGUEZ, EDWIN J · 2000 to 2022
$21.6M
Institute for Integration of Medicine & Science: A Partnership to Improve HealthUL1TR002645 · NCATS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CLARK, ROBERT A, HARGREAVES, KENNETH M · 2018 to 2022
$20.4M
Institute for Integration of Medicine & Science: A Partnership to Improve HealthUL1TR001120 · NCATS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CLARK, ROBERT A, HARGREAVES, KENNETH M · 2013 to 2017
$16.5M
NCATS NIH HHS UL1 TR001120NCATS NIH HHS UL1 TR002645NIGMS NIH HHS R25 GM060655
6 · The paper itself

Abstract

Since its original isolation in 2009,

Indexed as

Antifungal AgentsAzolesBiofilmsCandidaDrug RepositioningDrug Resistance, Multiple, FungalIsoindolesOrganoselenium CompoundsAntifungal AgentsAzolesebselenIsoindolesOrganoselenium CompoundsantifungalsCandida auriscandidiasisPrestwick libraryrepurposing

Identifiers

PMID30104269
PMCPMC6153848
OpenAlexW2885698573

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.