Evidence map›Paper›PMID 30103805›Full record

ArticleBMC research notes2018

Diagnostic accuracy of fine needle aspiration biopsy in pediatric small round cell tumors.

Marrium Asim, Ghazala Mudassir, Atif Ali Hashmi, Mariam Abid, Ahmareen Khalid Sheikh, Hania Naveed, Maryam Habib, Muhammad Muzzammil Edhi, Amir Khan

Open access · goldAbstract read
In one paragraph

Article in BMC research notes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Non Hodgkin Lymphoma Among Children: Pathological Aspects and Diagnostic Challenges.Clinical pathology (Thousand Oaks, Ventura County, Calif.)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Marrium AsimPakistan Institute of Medical Sciences, Islamabad, Pakistan.
Ghazala MudassirShifa College of Medicine, Islamabad, Pakistan.
Atif Ali HashmiLiaquat National Hospital and Medical College, Karachi, Pakistan.
Mariam AbidShifa College of Medicine, Islamabad, Pakistan.
Ahmareen Khalid SheikhPakistan Institute of Medical Sciences, Islamabad, Pakistan.
Hania NaveedShifa College of Medicine, Islamabad, Pakistan.
Maryam HabibShifa College of Medicine, Islamabad, Pakistan.
Muhammad Muzzammil EdhiBrown University, Providence, RI, USA.
Amir KhanKandahar University, Kandahar, Afghanistan. dramirkhan04@gmail.com.ORCID http://orcid.org/0000-0002-8763-7690
Pakistan Institute of Medical Sciences · PKBrown University · USKandahar University · AFLiaquat National Hospital · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveFine needle aspiration biospy (FNAB) is a simple, cost effective procedure, which can be carried out in the out-patient department. The objective of our study was to determine the diagnostic accuracy of fine needle aspiration biopsy in small round cell tumors of childhood, keeping histopathology as the gold standard.

resultsOut of these 50 cases, 35 (70%) were small round cell tumors and 15 (30%) cases of other childhood malignancies and certain reactive conditions. In our study, the most common malignant small round cell tumor (SRCT) on histopathology was Wilms tumor (10 cases) followed by non Hodgkin lymphoma (9 cases). FNAB results were correlated with the histological findings and the diagnostic accuracy of SRCT came out to be 98%. The sensitivity and specificity of FNAB in diagnosing SRCT was 97% and 100% respectively. FNAB was found to be a very useful technique in the initial evaluation of any palpable lesion of childhood. Although the small round cell tumors appear cytologically similar, in the hands of experienced cytopathologists, the subtle morphological features can help towards the final diagnosis. In addition, clinical and radiological findings are invaluable assets, which help to reach the final diagnosis.

Indexed as

Biopsy, Fine-NeedleAdolescentChildChild, PreschoolFemaleHumansImmunohistochemistryInfantInfant, NewbornLymphoma, Non-HodgkinMalePakistanSensitivity and SpecificityWilms TumorFine needle aspirationLymphomaMalignant small round cell tumorsNeuroblastomaRhabdomyosarcomaWilms tumor

Identifiers

PMID30103805
PMCPMC6090781
OpenAlexW2885333953

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.