Evidence map›Paper›PMID 30103679›Full record

Trial reportBMC anesthesiology2018

Evaluation of the effects of dexmedetomidine infusion on oxygenation and lung mechanics in morbidly obese patients with restrictive lung disease.

Ahmed Hasanin, Kareem Taha, Bassant Abdelhamid, Ayman Abougabal, Mohamed Elsayad, Amira Refaie, Sarah Amin, Shaimaa Wahba, Heba Omar, Mohamed Maher Kamel and 2 more

3 registry-linked trialsOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC anesthesiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02843698 phase4completednot on this map

Effects of Dexmedetomidine on Oxygenation and Lung Mechanics in Morbidly Obese Patients Undergoing Bariatric Operations: A Randomized Controlled Trial

TypeinterventionalSponsorCairo UniversityRan2016 to 2017Enrolled42ConditionsRestrictive Lung DiseaseArmsDexmedetomidine, Normal saline
NCT06207331 naterminatednot on this mapstarted 2023, after this paper: background citation

Effects of Atomized Dexmedetomidine on Lung Function in Patients With Chronic Obstructive Pulmonary Disease

TypeinterventionalSponsorThe Second Affiliated Hospital of Chongqing Medical UniversityRan2023 to 2024Enrolled6ConditionsRespiratory Function Tests, Chronic Obstructive Pulmonary Disease, DexmedetomidineArmsDexmedetomidine 0.5 μg/kg, Dexmedetomidine 1 μg/kg, Saline
NCT07385898 nacompletednot on this mapstarted 2023, after this paper: background citation

Effect of Dexmedetomidine on Lung Protection in Elderly Patients Undergoing Laparoscopic Surgery for Colorectal Cancer

TypeinterventionalSponsorThe Second Affiliated Hospital of Chongqing Medical UniversityRan2023 to 2024Enrolled64ConditionsRectal Tumors, Tumor of Sigmoid Colon, Lung Injury, Surgery, LaparoscopicArmsDexmedetomidine, Normal saline
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Review
  7. Article
  8. Dexmedetomidine as a Short-Use Analgesia for the Immature Nervous System.International journal of molecular sciences · 2024
    Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Ultrasound evaluation of inferior vena cava compression in tilted and supine term parturients.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2021
    Observational
  16. Article
  17. Article
  18. Article
  19. Respiratory and hemodynamic effects of 2 protocols of low-dose infusion of dexmedetomidine in dogs under isoflurane anesthesia.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Ahmed HasaninDepartment of anesthesia and critical care medicine, Cairo university, 01 elsarayah street, Elmanyal, Cairo, 11559, Egypt. ahmedmohamedhasanin@gmail.com.ORCID 0000-0001-9947-5863
Kareem TahaDepartment of anesthesia and critical care medicine, Cairo university, 01 elsarayah street, Elmanyal, Cairo, 11559, Egypt.
Bassant AbdelhamidDepartment of anesthesia and critical care medicine, Cairo university, 01 elsarayah street, Elmanyal, Cairo, 11559, Egypt.
Ayman AbougabalDepartment of anesthesia and critical care medicine, Cairo university, 01 elsarayah street, Elmanyal, Cairo, 11559, Egypt.
Mohamed ElsayadDepartment of anesthesia and critical care medicine, Cairo university, 01 elsarayah street, Elmanyal, Cairo, 11559, Egypt.
Amira RefaieDepartment of anesthesia and critical care medicine, Cairo university, 01 elsarayah street, Elmanyal, Cairo, 11559, Egypt.
Sarah AminDepartment of anesthesia and critical care medicine, Cairo university, 01 elsarayah street, Elmanyal, Cairo, 11559, Egypt.
Shaimaa WahbaDepartment of anesthesia and critical care medicine, Cairo university, 01 elsarayah street, Elmanyal, Cairo, 11559, Egypt.
Heba OmarDepartment of anesthesia and critical care medicine, Cairo university, 01 elsarayah street, Elmanyal, Cairo, 11559, Egypt.
Mohamed Maher KamelDepartment of anesthesia and critical care medicine, Cairo university, 01 elsarayah street, Elmanyal, Cairo, 11559, Egypt.
Yaser AbdelwahabDepartment of anesthesia and critical care medicine, Cairo university, 01 elsarayah street, Elmanyal, Cairo, 11559, Egypt.
Shereen M AminDepartment of anesthesia and critical care medicine, Cairo university, 01 elsarayah street, Elmanyal, Cairo, 11559, Egypt.
Cairo University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDexmedetomidine infusion improves oxygenation and lung mechanics in patients with chronic obstructive lung disease; however, its effect in patients with restrictive lung disease has not been thoroughly investigated yet. The aim of this work was to evaluate the effects of dexmedetomidine infusion on oxygenation and lung mechanics in morbidly obese patients with restrictive lung disease.

methodsForty-two morbidly obese patients scheduled for bariatric surgery were included in the study. Patients were randomized to receive either dexmedetomidine infusion at a bolus dose of 1mcg/Kg followed by infusion at 1 mcg/Kg/hour for 90 min (Dexmedetomidine group), or normal saline infusion (Control group). Both groups were compared with regard to: oxygenation {P/F ratio: PaO

resultsDexmedetomidine group showed significant improvement of the PaO

conclusionA 90-min dexmedetomidine infusion resulted in moderate improvement in oxygenation and lung mechanics in morbidly obese patients with restrictive lung disease.

trial registrationclinicaltrials.gov : NCT02843698 on 20 July 2016.

Indexed as

AdultBariatric SurgeryDexmedetomidineDouble-Blind MethodFemaleHemodynamicsHumansHypnotics and SedativesInfusions, IntravenousLungMaleObesity, MorbidOxygenPulmonary Disease, Chronic ObstructiveYoung AdultDexmedetomidineHypnotics and SedativesOxygenDexmedetomidineMorbidly obeseOxygenation

Identifiers

PMID30103679
PMCPMC6090793
OpenAlexW2887144438

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.