ArticleBMC genomics2018
Identification and characterization of ncRNA-associated ceRNA networks in Arabidopsis leaf development.
Article in BMC genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
30 citing papers in PubMed, 76 citations in OpenAlex.
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- Integrative analysis of coding and non-coding RNAs in rice reveals conserved molecular response signatures to heat, drought, and salt stresses.Journal of biosciences · 2025Article
- Source leaves are regulated by sink strengths through non-coding RNAs and alternative polyadenylation in cucumber (Cucumis sativus L.).BMC plant biology · 2024Article
- Identification and Characterisation of the CircRNAs Involved in the Regulation of Leaf Colour inBiology · 2024Article
- The Construction of lncRNA/circRNA-miRNA-mRNA Networks Reveals Functional Genes Related to Growth Traits inInternational journal of molecular sciences · 2024Article
- Full-length transcriptome characterization ofFrontiers in genetics · 2024Article
- The ncRNAs Involved in the Regulation of Abiotic Stress-Induced Anthocyanin Biosynthesis in Plants.Antioxidants (Basel, Switzerland) · 2023Review
- Spatiotemporal miRNA and transcriptomic network dynamically regulate the developmental and senescence processes of poplar leaves.Horticulture research · 2023Article
- Roles of long non-coding RNAs in plant immunity.PLoS pathogens · 2023Review
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- Identification and characterization of CircRNA-associated CeRNA networks in moso bamboo under nitrogen stress.BMC plant biology · 2023Article
- Identification, biogenesis, function, and mechanism of action of circular RNAs in plants.Plant communications · 2023Review
- Plant long non-coding RNAs: identification and analysis to unveil their physiological functions.Frontiers in plant science · 2023Review
- Integrative Investigation of Root-Related mRNAs, lncRNAs and circRNAs of "Muscat Hamburg" (Genes · 2022Article
- The Characters of Non-Coding RNAs and Their Biological Roles in Plant Development and Abiotic Stress Response.International journal of molecular sciences · 2022Review
- Expression rewiring and methylation of non-coding RNAs involved in rhizome phenotypic variations of lotus ecotypes.Computational and structural biotechnology journal · 2022Article
- Whole-Transcriptome Analysis Reveals Autophagy Is Involved in Early Senescence ofFrontiers in plant science · 2022Article
- Circular RNAs acting as ceRNAs mediated by miRNAs may be involved in the synthesis of soybean fatty acids.Functional & integrative genomics · 2021Article
- Analysis of Rice Transcriptome Reveals the LncRNA/CircRNA Regulation in Tissue Development.Rice (New York, N.Y.) · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundLeaf development is a complex biological process that is accompanied by wide transcriptional changes. Many protein-coding genes have been characterized in plant leaves, but little attention has been given to noncoding RNAs (ncRNAs). Moreover, increasing evidence indicates that an intricate interplay among RNA species, including protein-coding RNAs and ncRNAs, exists in eukaryotic transcriptomes, however, it remains elusive in plant leaves.
resultsWe detected novel ncRNAs, such as circular RNAs (circRNAs) and long noncoding RNAs (lncRNAs), and further constructed and analyzed their associated competitive endogenous RNA (ceRNA) networks in Arabidopsis leaves. Transcriptome profiling showed extensive changes during leaf development. In addition, comprehensive detection of circRNAs in other plant leaves suggested that circRNAs are widespread in plant leaves. To investigate the complex post-transcriptional interactions in Arabidopsis leaves, we constructed a global circRNA/lncRNA-associated ceRNA network. Functional analysis revealed that ceRNAs were highly correlated with leaf development. These ceRNAs could be divided into six clusters, which were enriched for different functional classes. Stage-specific ceRNA networks were further constructed and comparative analysis revealed different roles of stage common and specific hub ceRNAs.
conclusionsOur results demonstrate that understanding the ceRNA interactions will lead insights into gene regulations implicated in leaf development.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.