Evidence map›Paper›PMID 30103655›Full record

ArticleJournal of empirical research on human research ethics : JERHRE2018

Adolescents' and Parents' Attitudes Toward Adolescent Clinical Trial Participation: Changes Over One Year.

Rebecca K Tsevat, Carmen Radecki Breitkopf, Sara E Landers, Ariel M de Roche, Christine Mauro, Lisa S Ipp, Marina Catallozzi, Susan L Rosenthal

Abstract read
In one paragraph

Article in Journal of empirical research on human research ethics : JERHRE, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Attitudes of Mothers Regarding Willingness to Enroll Their Children in Research.Journal of empirical research on human research ethics : JERHRE · 2020
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rebecca K Tsevat1 Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.
Carmen Radecki Breitkopf2 Mayo Clinic, Rochester, MN, USA.
Sara E Landers1 Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.
Ariel M de Roche1 Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.
Christine Mauro3 Columbia University, Mailman School of Public Health, New York, NY, USA.
Lisa S Ipp4 NewYork-Presbyterian Hospital, New York, NY, USA.
Marina Catallozzi1 Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.
Susan L Rosenthal1 Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.

Funding

Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
Clinical and Translational Science CenterUL1TR000457 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI IMPERATO-MCGINLEY, JULIANNE L · 2012 to 2016
$46.0M
Clinical and Translational Science AwardUL1TR000040 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2012 to 2015
$26.2M
Adolescent and Parental Attitudes About STI Prevention Trial ParticipationR01HD067287 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ROSENTHAL, SUSAN L · 2011 to 2015
$2.8M
NCATS NIH HHS UL1 TR000040NCATS NIH HHS UL1 TR000457NCATS NIH HHS UL1 TR002384NICHD NIH HHS R01 HD067287
6 · The paper itself

Abstract

Little is known about how adolescents' and parents' thoughts about participation in clinical trials change over time. In this study, adolescent (14-17 years)-parent dyads were asked about willingness to participate in a hypothetical reproductive health study. A year later, they were asked how their thoughts about the study had changed. Qualitative responses were coded and analyzed using framework analysis. Thirty-two percent of adolescents and 18% of parents reported changes in thoughts; reasons included general changes in perception, clearer understanding, new knowledge or experiences, increased maturity/age of adolescents, and changes in participants independent of the study. Adolescents and parents may benefit from learning about studies multiple times, and investigators should account for development and new experiences to optimize adolescent research enrollment.

Indexed as

AttitudeBiomedical ResearchInformed ConsentParentsAdolescentAdolescent BehaviorAdolescent DevelopmentAge FactorsComprehensionFemaleHealth Knowledge, Attitudes, PracticeHumansInformed Consent By MinorsMaleQualitative ResearchReproductive Healthadolescent healthclinical trialsdecision-makingparental influencereproductive health

Identifiers

PMID30103655
PMCPMC6146060

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.