Evidence map›Paper›PMID 30103486›Full record

ArticleNutrients2018

Ultraviolet Irradiation of Skin Alters the Faecal Microbiome Independently of Vitamin D in Mice.

Simon Ghaly, Nadeem O Kaakoush, Frances Lloyd, Lavinia Gordon, Cynthia Forest, Ian C Lawrance, Prue H Hart

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 39 citations in OpenAlex.

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  15. Vitamin D, gut microbiota, and radiation-related resistance: a love-hate triangle.Journal of experimental & clinical cancer research : CR · 2019
    Review
  16. Temperature as a modulator of the gut microbiome: what are the implications and opportunities for thermal medicine?International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2019
    Review
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Simon GhalyTelethon Kids Institute, The University of Western Australia, Perth, WA 6008, Australia. simon.ghaly@research.uwa.edu.au.ORCID 0000-0003-2489-6430
Nadeem O KaakoushSchool of Medical Sciences, UNSW Sydney, Kensington, NSW 2033, Australia. n.kaakoush@unsw.edu.au.
Frances LloydSchool of Medicine and Pharmacology, The University of Western Australia, Perth, WA 6009, Australia. frances.p.lloyd8@gmail.com.
Lavinia GordonAustralian Genome Research Facility, The Walter and Eliza Hall Institute, Parkville, VIC 3052, Australia. Lavinia.Gordon@agrf.org.au.
Cynthia ForestDepartment of Anatomical Pathology, PathWest, Fiona Stanley Hospital, Murdoch, WA 6150, Australia. Cindy.Forrest@health.wa.gov.au.
Ian C LawranceSchool of Medicine and Pharmacology, The University of Western Australia, Perth, WA 6009, Australia. ian.lawrance@uwa.edu.au.
Prue H HartTelethon Kids Institute, The University of Western Australia, Perth, WA 6008, Australia. prue.hart@telethonkids.org.au.ORCID 0000-0001-7207-6467
The Kids Research Institute Australia · AUFiona Stanley Hospital · AUSt John of God Subiaco Hospital · AUThe University of Western Australia · AUUNSW Sydney · AUWalter and Eliza Hall Institute of Medical Research · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reduced sunlight exposure has been associated with an increased incidence of Crohn's disease and ulcerative colitis. The effect of ultraviolet radiation (UVR) on the faecal microbiome and susceptibility to colitis has not been explored. C57Bl/6 female mice were fed three different vitamin D-containing diets for 24 days before half of the mice in each group were UV-irradiated (1 kJ/m²) for each of four days, followed by twice-weekly irradiation of shaved dorsal skin for 35 days. Faecal DNA was extracted and high-throughput sequencing of the 16S RNA gene performed. UV irradiation of skin was associated with a significant change in the beta-diversity of faeces compared to nonirradiated mice, independently of vitamin D. Specifically, members of phylum Firmicutes, including

Indexed as

Ultraviolet RaysAnimal FeedAnimalsBacteriaCholecalciferolColitisCytokinesDextran SulfateDisease Models, AnimalFecesFemaleGastrointestinal MicrobiomeInflammation MediatorsMice, Inbred C57BLSkinCholecalciferolCytokinesDextran SulfateInflammation Mediatorsinflammatory bowel diseasemicrobiomeultraviolet radiationvitamin D

Identifiers

PMID30103486
PMCPMC6116187
OpenAlexW2886086186

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.