Evidence map›Paper›PMID 30103442›Full record

ArticleNanomaterials (Basel, Switzerland)2018

Markers of Oxidative Stress in the Exhaled Breath Condensate of Workers Handling Nanocomposites.

Daniela Pelclova, Vladimir Zdimal, Jaroslav Schwarz, Stepanka Dvorackova, Martin Komarc, Jakub Ondracek, Martin Kostejn, Petr Kacer, Stepanka Vlckova, Zdenka Fenclova and 4 more

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  6. Review
  7. Review
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  11. NanoTiONanomaterials (Basel, Switzerland) · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Daniela PelclovaDepartment of Occupational Medicine, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Na Bojisti 1, 128 00 Prague 2, Czech Republic. daniela@pelclova.cz.ORCID 0000-0002-0240-5146
Vladimir ZdimalInstitute of Chemical Process Fundamentals of the CAS, Rozvojová 1/135, 165 02 Prague 6, Czech Republic. zdimal@icpf.cas.cz.ORCID 0000-0002-8167-1804
Jaroslav SchwarzInstitute of Chemical Process Fundamentals of the CAS, Rozvojová 1/135, 165 02 Prague 6, Czech Republic. schwarz@icpf.cas.cz.
Stepanka DvorackovaDepartment of Machining and Assembly, Department of Engineering Technology, Department of Material Science, Faculty of Mechanical Engineering, Technical University in Liberec, Faculty of Mechanical Engineering, Studentská 1402/2, 461 17 Liberec, Czech Republic. stepanka.dvorackova@tul.cz.
Martin KomarcInstitute of Biophysics and Informatics, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Salmovská 1, 120 00 Prague 2, Czech Republic. martin.komarc@lf1.cuni.cz.
Jakub OndracekInstitute of Chemical Process Fundamentals of the CAS, Rozvojová 1/135, 165 02 Prague 6, Czech Republic. ondracek@icpf.cas.cz.
Martin KostejnInstitute of Chemical Process Fundamentals of the CAS, Rozvojová 1/135, 165 02 Prague 6, Czech Republic. kostejn@icpf.cas.cz.ORCID 0000-0003-3825-2636
Petr KacerBiocev, 1st Faculty of Medicine, Charles University, Prumyslova 595, 252 50 Vestec, Czech Republic. petr.kacer69@gmail.com.
Stepanka VlckovaDepartment of Occupational Medicine, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Na Bojisti 1, 128 00 Prague 2, Czech Republic. Stepanka.Vlckova@vfn.cz.
Zdenka FenclovaDepartment of Occupational Medicine, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Na Bojisti 1, 128 00 Prague 2, Czech Republic. zdenka.fenclova@lf1.cuni.cz.
Alexey PopovDepartment of Machining and Assembly, Department of Engineering Technology, Department of Material Science, Faculty of Mechanical Engineering, Technical University in Liberec, Faculty of Mechanical Engineering, Studentská 1402/2, 461 17 Liberec, Czech Republic. alespopov@yandex.ru.
Lucie LischkovaDepartment of Occupational Medicine, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Na Bojisti 1, 128 00 Prague 2, Czech Republic. Lucie.Lischkova@vfn.cz.
Sergey ZakharovDepartment of Occupational Medicine, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Na Bojisti 1, 128 00 Prague 2, Czech Republic. Sergej.Zacharov@vfn.cz.
Dhimiter BelloDepartment of Biomedical and Nutritional Sciences, Zuckerberg College of Health Sciences, Lowell, MA 01854, USA. Dhimiter_Bello@uml.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Researchers in nanocomposite processing may inhale a variety of chemical agents, including nanoparticles. This study investigated airway oxidative stress status in the exhaled breath condensate (EBC). Nineteen employees (42.4 ± 11.4 y/o), working in nanocomposites research for 18.0 ± 10.3 years were examined pre-shift and post-shift on a random workday, together with nineteen controls (45.5 ± 11.7 y/o). Panels of oxidative stress biomarkers derived from lipids, nucleic acids, and proteins were analyzed in the EBC. Aerosol exposures were monitored during three major nanoparticle generation operations: smelting and welding (workshop 1) and nanocomposite machining (workshop 2) using a suite of real-time and integrated instruments. Mass concentrations during these operations were 0.120, 1.840, and 0.804 mg/m³, respectively. Median particle number concentrations were 4.8 × 10⁴, 1.3 × 10⁵, and 5.4 × 10⁵ particles/cm³, respectively. Nanoparticles accounted for 95, 40, and 61%, respectively, with prevailing Fe and Mn. All markers of nucleic acid and protein oxidation, malondialdehyde, and aldehydes C₆⁻C

Indexed as

exhaled breath condensateinhalationnanocompositesnanoparticlesoccupational exposureoxidative stressworkers

Identifiers

PMID30103442
PMCPMC6116291

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.