Evidence map›Paper›PMID 30103376›Full record

ArticleSensors (Basel, Switzerland)2018

Validation of the Apple Watch for Heart Rate Variability Measurements during Relax and Mental Stress in Healthy Subjects.

David Hernando, Surya Roca, Jorge Sancho, Álvaro Alesanco, Raquel Bailón

2 registry-linked trialsAbstract readValidation Study
In one paragraph

Article in Sensors (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 100 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
100citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04510779 nacompletednot on this mapstarted 2022, after this paper: background citation

Monitoring Heart Failure Patients Using Heart Rate Variability Measured by the Apple Watch

TypeinterventionalSponsorTufts Medical CenterRan2022 to 2023Enrolled10ConditionsHeart FailureArmsApple Watch
NCT05090995 nacompletednot on this mapstarted 2022, after this paper: background citation

A Photoplethysmography Sensor-based Personalized Feedback Intervention for Heavy-drinking Young Adults Targeting Heart Rate Variability, Resting Heart Rate, and Sleep

TypeinterventionalSponsorYale UniversityRan2022 to 2023Enrolled60ConditionsHeavy Drinking, Harmful, Use, AlcoholArmsBehavioral Self-Management and Feedback, Behavioral Self-Management
3 · Its place in the literature

Who cites it

100 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  14. Assessing Stress Level Scores Against Wearables-Driven Physiological Measurements.Stress and health : journal of the International Society for the Investigation of Stress · 2025
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  18. Observational
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40 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

David HernandoBiomedical Signal Interpretation & Computational Simulation (BSICoS) Group, Aragón Institute of Engineering Research (I3A), IIS Aragón, University of Zaragoza, 50018 Zaragoza, Spain. dhernand@unizar.es.ORCID 0000-0002-1462-4880
Surya RocaCommunications Networks and Information Technologies (CeNIT) Group, Aragón Institute of Engineering Research (I3A), University of Zaragoza, 50018 Zaragoza, Spain. surya@unizar.es.
Jorge SanchoCommunications Networks and Information Technologies (CeNIT) Group, Aragón Institute of Engineering Research (I3A), University of Zaragoza, 50018 Zaragoza, Spain. jslarraz@unizar.es.ORCID 0000-0001-8518-6884
Álvaro AlesancoCommunications Networks and Information Technologies (CeNIT) Group, Aragón Institute of Engineering Research (I3A), University of Zaragoza, 50018 Zaragoza, Spain. alesanco@unizar.es.ORCID 0000-0002-5254-1402
Raquel BailónBiomedical Signal Interpretation & Computational Simulation (BSICoS) Group, Aragón Institute of Engineering Research (I3A), IIS Aragón, University of Zaragoza, 50018 Zaragoza, Spain. rbailon@unizar.es.ORCID 0000-0003-1272-0550

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heart rate variability (HRV) analysis is a noninvasive tool widely used to assess autonomic nervous system state. The market for wearable devices that measure the heart rate has grown exponentially, as well as their potential use for healthcare and wellbeing applications. Still, there is a lack of validation of these devices. In particular, this work aims to validate the Apple Watch in terms of HRV derived from the RR interval series provided by the device, both in temporal (HRM (mean heart rate), SDNN, RMSSD and pNN50) and frequency (low and high frequency powers, LF and HF) domain. For this purpose, a database of 20 healthy volunteers subjected to relax and a mild cognitive stress was used. First, RR interval series provided by Apple Watch were validated using as reference the RR interval series provided by a Polar H7 using Bland-Altman plots and reliability and agreement coefficients. Then, HRV parameters derived from both RR interval series were compared and their ability to identify autonomic nervous system (ANS) response to mild cognitive stress was studied. Apple Watch measurements presented very good reliability and agreement (>0.9). RR interval series provided by Apple Watch contain gaps due to missing RR interval values (on average, 5 gaps per recording, lasting 6.5 s per gap). Temporal HRV indices were not significantly affected by the gaps. However, they produced a significant decrease in the LF and HF power. Despite these differences, HRV indices derived from the Apple Watch RR interval series were able to reflect changes induced by a mild mental stress, showing a significant decrease of HF power as well as RMSSD in stress with respect to relax, suggesting the potential use of HRV measurements derived from Apple Watch for stress monitoring.

Indexed as

Autonomic Nervous SystemHealthy VolunteersHeart RateHumansMonitoring, AmbulatoryReproducibility of ResultsStress, PsychologicalWearable Electronic DevicesANS assessmentApple Watchheart rate variabilityRR seriesvalidationwearable device

Identifiers

PMID30103376
PMCPMC6111985

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.