ArticleJournal of neuromuscular diseases
MRI-Guided Biopsy as a Tool for Diagnosis and Research of Muscle Disorders.
Article in Journal of neuromuscular diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- FSHD muscle shows perturbation in fibroadipogenic progenitor cells, mitochondrial function and alternative splicing independently of inflammation.Human molecular genetics · 2024Pooled it
- Muscle biopsy practices in the evaluation of neuromuscular disease: A systematic literature review.Neuropathology and applied neurobiology · 2023Pooled it
- Immunohistological and electron microscopy profile of unique TIRM-MRI guided muscle biopsies of FSHD patients.Journal of neuromuscular diseases · 2026Article
- Semi-quantitative analyses of muscle magnetic resonance imaging for pattern recognition in early idiopathic inflammatory myopathies.Journal of neuromuscular diseases · 2026Article
- Ultrasound-guided skeletal muscle biopsy technique permits measurement of structural, functional, cellular and biochemical properties.Scientific reports · 2026Article
- IL-6 and TNF are Potential Inflammatory Biomarkers in Facioscapulohumeral Muscular Dystrophy.Journal of neuromuscular diseases · 2024Article
- The utility and tolerability of ultrasound guided muscle biopsy in the investigation of myopathy: a follow-up study.Journal of ultrasound · 2023Article
- The double homeodomain protein DUX4c is associated with regenerating muscle fibers and RNA-binding proteins.Skeletal muscle · 2023Article
- Facioscapulohumeral dystrophy transcriptome signatures correlate with different stages of disease and are marked by different MRI biomarkers.Scientific reports · 2022Article
- Three-dimensional quantitative muscle ultrasound in a healthy population.Muscle & nerve · 2021Article
- Reduced specific force in patients with mild and severe facioscapulohumeral muscular dystrophy.Muscle & nerve · 2021Article
- How Imaging Can Assist with Diagnosis and Monitoring of Disease in Myositis.Current rheumatology reports · 2020Review
- Preserved single muscle fiber specific force in facioscapulohumeral muscular dystrophy.Neurology · 2020Article
- Severe proximal muscle weakness with normal CK as a presenting feature of ANCA-associated vasculitis.BMJ case reports · 2020Article
- Correlation Between Quantitative MRI and Muscle Histopathology in Muscle Biopsies from Healthy Controls and Patients with IBM, FSHD and OPMD.Journal of neuromuscular diseases · 2020Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSampling error is a common problem in muscle biopsies. MRI-guided biopsy allows verification of biopsy site during the procedure, which may reduce sampling error in patients with focal disease.
objectivesTo describe the technique for MRI-guided muscle biopsy and discuss potential applications.
methodsAxial MRI images were acquired to determine the target site for muscle biopsy. Needle trajectory was planned on 3D T1 weighted imaging and a MRI-guided biopsy of the vastus lateralis was performed in 13 FSHD patients.
resultsAn adequate amount of muscle tissue was obtained in all participants, and MRI-guided biopsy succeeded in reaching focal target sites. However, symptomatic hematomas were observed in 2/13 patientsDiscussion:MRI-guided biopsy has a higher complication rate compared to traditional needle biopsy, most likely due to proximity to blood vessels in combination with the vacuum-assisted suction of the MRI-guided technique. We recommend that this technique is reserved for select diagnostic cases and research questions, with careful assessment of vasculature and reduced suction levels.
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