ArticleJournal of Huntington's disease2018
Huntington's Disease Clinical Trials Corner: August 2018.
Article in Journal of Huntington's disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Creatine Safety, Tolerability, & Efficacy in Huntington's Disease (CREST-E)
A Phase 2, Multi-center, Randomized, Double-blind, Placebo Controlled Study in Subjects With Late Prodromal and Early Manifest Huntington's Disease to Assess the Safety, Tolerability, pk, and Efficacy of Pepinemab
Who cites it
14 citing papers in PubMed.
- Huntington's disease clinical trials update: October 2025.Journal of Huntington's disease · 2026Review
- Huntington's disease clinical trials update: March 2025.Journal of Huntington's disease · 2025Review
- Huntington's Disease Clinical Trials Corner: March 2024.Journal of Huntington's disease · 2024Article
- Huntington's Disease Clinical Trials Corner: August 2023.Journal of Huntington's disease · 2023Article
- Utility of the Huntington's Disease Prognostic Index Score for a Perimanifest Clinical Trial.Movement disorders : official journal of the Movement Disorder Society · 2022Article
- Current and Possible Future Therapeutic Options for Huntington's Disease.Journal of central nervous system disease · 2022Review
- Therapeutic Potential of Human Stem Cell Implantation in Alzheimer's Disease.International journal of molecular sciences · 2021Review
- svReg: Structural varying-coefficient regression to differentiate how regional brain atrophy affects motor impairment for Huntington disease severity groups.Biometrical journal. Biometrische Zeitschrift · 2021Article
- Neuroimmune crosstalk and evolving pharmacotherapies in neurodegenerative diseases.Immunology · 2021Review
- Hybrid 2-[18F] FDG PET/MRI in premanifest Huntington's disease gene-expansion carriers: The significance of partial volume correction.PloS one · 2021Article
- Reactive Species in Huntington Disease: Are They Really the Radicals You Want to Catch?Antioxidants (Basel, Switzerland) · 2020Review
- Robust Markers and Sample Sizes for Multicenter Trials of Huntington Disease.Annals of neurology · 2020Article
- Neurons under genetic control: What are the next steps towards the treatment of movement disorders?Computational and structural biotechnology journal · 2020Review
- Huntington's Disease Clinical Trials Corner: June 2019.Journal of Huntington's disease · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
In the third edition of the Huntington's Disease Clinical Trials Corner we list all currently registered and ongoing clinical trials, expand on the SIGNAL trial (NCT02481674), and cover the recently finished CREST-E trial (NCT00712426).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.