ArticleInternational journal for parasitology. Drugs and drug resistance2018
Modelling anthelmintic resistance by extending eggCounts package to allow individual efficacy.
Article in International journal for parasitology. Drugs and drug resistance, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 75 citations in OpenAlex.
- Increasing importance of anthelmintic resistance in European livestock: creation and meta-analysis of an open database.Parasite (Paris, France) · 2020Pooled it
- Evaluation of Different Benzimidazole Formulations Against Sheep Naturally Infected withVeterinary sciences · 2026Article
- Variability in the anthelmintic efficacy of levamisole against gastrointestinal nematodes of cattle, sheep and goats in South Darfur, Sudan.BMC veterinary research · 2026Article
- Old world camels in Germany: parasitic nematode communities characterized by nemabiome analysis showed reduced anthelmintic efficacy according to the fecal egg count reduction test.Parasites & vectors · 2025Article
- Article
- Anthelmintic resistance against benzimidazoles and macrocyclic lactones in strongyle populations on cattle farms in northern Germany.Scientific reports · 2025Article
- Occurrence of Internal Parasites and Anthelmintic Resistance in Goats.Animals : an open access journal from MDPI · 2025Article
- Chromosomal genome assembly resolves drug resistance loci in the parasitic nematode Teladorsagia circumcincta.PLoS pathogens · 2025Article
- Gastrointestinal parasitic worm burdens and efficacy of deworming practices in growing beef cattle grazing California pastures.Translational animal science · 2025Article
- Unravelling the Effectiveness of Anthelmintic Treatments on Equine Strongyles on Irish Farms.Animals : an open access journal from MDPI · 2024Article
- Patterns of Equine Small Strongyle Species Infection after Ivermectin Intervention in Thailand: Egg Reappearance Period and Nemabiome Metabarcoding Approach.Animals : an open access journal from MDPI · 2024Article
- First evaluation and detection of ivermectin resistance in gastrointestinal nematodes of sheep and goats in South Darfur, Sudan.PloS one · 2024Article
- Efficacy of flukicides against Fasciola hepatica and first report of triclabendazole resistance on German sheep farms.International journal for parasitology. Drugs and drug resistance · 2023Article
- Multiple anthelmintic drug resistant Ancylostoma caninum in foxhounds.International journal for parasitology. Drugs and drug resistance · 2023Article
- Endoparasite loads and the efficacy of conventional anthelmintics against gastrointestinal nematodes in captive European bison.International journal for parasitology. Parasites and wildlife · 2023Article
- Species interactions, stability, and resilience of the gut microbiota - Helminth assemblage in horses.iScience · 2023Article
- Investigation of the Efficacy of Pyrantel Pamoate, Mebendazole, Albendazole, and Ivermectin againstAnimals : an open access journal from MDPI · 2022Article
- Assessment of effectiveness of deworming options in recently weaned beef cattle utilizing different anthelmintic programs in the southeast.Translational animal science · 2022Article
- Anthelmintic resistance of horse strongyle nematodes to fenbendazole in Lithuania.Acta veterinaria Scandinavica · 2022Article
- Equine strongylids: Ivermectin efficacy and fecal egg shedding patterns.Parasitology research · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The same anthelmintic treatment can have variable efficacy on individual animals even if the parasite population is homogenously susceptible. An extension of the R package eggCounts is proposed to take individual efficacy into account using a Bayesian hierarchical model. A simulation study is conducted to compare the performance of five different methods on estimating faecal egg count reduction and its uncertainty interval. Simulation results showed the individual efficacy model offered robust inference to two different data simulation procedures with low root mean squared error on the reduction estimate and appropriate uncertainty estimates. Different methods were used to evaluate the anthelmintic resistance in a dataset from USA with sheep and cattle faecal egg counts, where a strong anthelmintic resistance was detected. Open-source statistical tools were updated to include the proposed model.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.