ArticleJournal of psychiatric research2018
Efficacy of the Unified Protocol for transdiagnostic treatment of comorbid psychopathology accompanying emotional disorders compared to treatments targeting single disorders.
Article in Journal of psychiatric research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05734313 (Telemedicine-Delivered Unified Protocol for Cognitive Behavioral Therapy for Anxiety and Depression in Young Adults With Type 1 Diabetes), which is not on this map. Cited by 41 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Telemedicine-Delivered Unified Protocol for Cognitive Behavioral Therapy for Anxiety and Depression in Young Adults With Type 1 Diabetes
Who cites it
41 citing papers in PubMed, 2 syntheses or guidelines pooled it, 92 citations in OpenAlex.
- Widening the Reach: The Broad Impact of Unguided Self-Help for Eating Disorders.The International journal of eating disorders · 2025Pooled it
- Pooled it
- The Feasibility and Efficacy of a Group-Based, Brief Transdiagnostic Cognitive-Behavioral Treatment for Adolescents with Internalizing Problems.Child psychiatry and human development · 2025Trial
- Trial
- A comparison of transdiagnostic behavior therapy (TBT) and behavioral activation treatment for depression (BATD) in veterans with major depressive disorder.Journal of clinical psychology · 2022Trial
- The unified protocol as an internet-based intervention for emotional disorders: Randomized controlled trial.PloS one · 2022Trial
- Does the unified protocol really change neuroticism? Results from a randomized trial.Psychological medicine · 2021Trial
- Isolating the Effects of Mindfulness Training Across Anxiety Disorder Diagnoses in the Unified Protocol.Behavior therapy · 2020Trial
- Effectiveness of a Transdiagnostic Guided Internet-Delivered Protocol for Emotional Disorders Versus Treatment as Usual in Specialized Care: Randomized Controlled Trial.Journal of medical Internet research · 2020Trial
- Factor Structures of the Hospital Anxiety and Depression Scale in Cancer: Implications of Comprehensive Confirmatory Analysis on the German Version of the HADS in an Oncological Sample.Cancer medicine · 2026Article
- Cost-effectiveness and acceptability study of the Unified Protocol for the treatment of emotional disorders in brief groups in primary care services of the Spanish National Health System: a study protocol.BMC primary care · 2026Article
- Accelerated Unified Protocol for Transdiagnostic Treatment of Anxiety Disorders in a VHA System.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2026Article
- Efficacy of a personalized, response-based transdiagnostic intervention for emotional disorders delivered via the Internet: a protocol for an adaptive randomized controlled trial.Frontiers in psychiatry · 2026Article
- A mixed methods pilot feasibility study of the unified protocol group psychotherapy for early bipolar disorder.Frontiers in psychiatry · 2025Article
- Participants' evaluation of an internet-based group compassion-focused therapy program for young people in Sweden.Frontiers in psychology · 2025Article
- Article
- Effect of unified transdiagnostic treatment on negative affect, anxiety, and difficulties in emotional regulation in obese children: A randomized controlled trial.Journal of education and health promotion · 2025Article
- Article
- Randomized controlled trial investigating web-based, therapist delivered eye movement desensitization and reprocessing for adults with suicidal ideation.Frontiers in psychiatry · 2024Article
- Feasibility and Efficacy of Intensive Dialectical Behavior Therapy Skills Training in An Outpatient Setting for A Group of Patients with Extensive Care Needs - A Transdiagnostic Approach.The Psychiatric quarterly · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
objectiveThis study aimed to examine whether the Unified Protocol (UP), a transdiagnostic cognitive-behavioral therapy for emotional disorders (i.e., anxiety, mood, and related disorders), is efficacious in the treatment of co-occurring emotional disorders compared to established single disorder protocols (SDPs) that target specific disorders (e.g., panic disorder).
methodParticipants included 179 adults seeking outpatient psychotherapy. Participant age ranged from 18 to 66 years, with an average of 30.66 years (SD = 10.77). The sample was 55% female and mostly Caucasian (83%). Diagnostic assessments were completed with the Anxiety Disorder Interview Schedule (ADIS), and disorder-specific, clinician-rated measures for the comorbid diagnoses of interest.
resultsIn both treatment conditions, participants' mean number of diagnoses dropped significantly from baseline to posttreatment, and baseline to 12-month follow-up. Additionally, large effects were observed for changes in comorbid generalized anxiety (ES
conclusionsResults suggest that both the UP and SDPs are efficacious in reducing symptoms of comorbid emotional disorders. The clinical, practical, and cost-effective advantages of transdiagnostic CBT are discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.