ReviewSexually transmitted diseases2018
Centers for Disease Control and Prevention Syphilis Summit-Diagnostics and Laboratory Issues.
Review in Sexually transmitted diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 34 citations in OpenAlex.
- Improved efficiency using sequential automated immunoassays for syphilis screening in blood donors.Journal of clinical microbiology · 2024Article
- Lack of Serological Response by Delivery to Syphilis Treatment Does Not Impact Pregnancy Outcomes.Journal of clinical medicine · 2024Article
- Diagnosis and treatment of syphilitic uveitis: Taiwan experts consensus.Journal of the Chinese Medical Association : JCMA · 2024Article
- Prevalence and Predictors of Oral Treponema pallidum Detection by Quantitative Polymerase Chain Reaction in Early Syphilis.The Journal of infectious diseases · 2024Article
- CDC Laboratory Recommendations for Syphilis Testing, United States, 2024.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2024Article
- Evaluation of a minimal array ofMicrobiology spectrum · 2024Article
- Testing Technologies as Enhancers of Disease Intervention Specialist Activities: Applying Lessons From COVID-19.Sexually transmitted diseases · 2023Article
- Clinical analysis and methodological evaluation of syphilis infection in patients in a first-class tertiary hospital in Suzhou, China.American journal of clinical and experimental immunology · 2023Article
- Laboratory Evaluation of the DPP Syphilis Screen & Confirm Assay.Microbiology spectrum · 2022Article
- Incidence of syphilis infection and syphilis-related care utilization among adolescents and young adults living with HIV.International journal of STD & AIDS · 2022Article
- The Laboratory Diagnosis of Syphilis.Journal of clinical microbiology · 2021Review
- Immunological tests and their interpretation in uveitis.Indian journal of ophthalmology · 2020Review
- Who cares for syphilis? A cross-sectional study on diagnosis and treatment of syphilis by GPs in Amsterdam, the Netherlands.BJGP open · 2020Article
- A Veteran Presenting With Leg Swelling, Dyspnea, and Proteinuria.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Syphilis, caused by the bacterium Treponema pallidum, is on the rise in the United States particularly among men who have sex with men. The disease is complex with varied clinical manifestations and challenges remain in the laboratory diagnostic setting because T. pallidum is noncultivable and no single test can accurately diagnose all stages of the disease. There are missed opportunities for the use of direct detection tests in primary and secondary syphilis. The increasing use of different reverse sequence algorithms for serology testing without validation in populations with varying risks for syphilis makes the interpretation of test results difficult; this has led to concerns about diagnostic errors or overtreatment. On the other hand, the traditional algorithm may miss some early primary syphilis cases, which is of concern in high-risk populations. The potential utility of rapid syphilis serology tests in different settings or populations remains to be determined. The implementation of better tests and appropriate testing algorithms together with laboratory guidelines for test use in general will lead to better diagnostic options for syphilis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.