Evidence map›Paper›PMID 30102469›Full record

ArticleAdvanced healthcare materials2018

Enhancing Osteosarcoma Killing and CT Imaging Using Ultrahigh Drug Loading and NIR-Responsive Bismuth Sulfide@Mesoporous Silica Nanoparticles.

Yao Lu, Lihua Li, Zefeng Lin, Mei Li, Xiaoming Hu, Yu Zhang, Mingying Peng, Hong Xia, Gang Han

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Advanced healthcare materials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 47 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 1 synthesis or guideline pooled it, 121 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Yao LuDepartment of Orthopedics, Zhujiang Hospital, Southern Medical University, 253 Gongye Road, Guangzhou, 510282, China.
Lihua LiDepartment of Orthopedics, Guangdong Key Lab of Orthopedic Technology and Implant, Key Laboratory of Trauma & Tissue Repair of Tropical Area of PLA, Guangzhou General Hospital of Guangzhou Military Command of PLA, 111 Liuhua Road, Guangzhou, Guangdong, 510010, China.
Zefeng LinDepartment of Orthopedics, Guangdong Key Lab of Orthopedic Technology and Implant, Key Laboratory of Trauma & Tissue Repair of Tropical Area of PLA, Guangzhou General Hospital of Guangzhou Military Command of PLA, 111 Liuhua Road, Guangzhou, Guangdong, 510010, China.
Mei LiDepartment of Orthopedics, Guangdong Key Lab of Orthopedic Technology and Implant, Key Laboratory of Trauma & Tissue Repair of Tropical Area of PLA, Guangzhou General Hospital of Guangzhou Military Command of PLA, 111 Liuhua Road, Guangzhou, Guangdong, 510010, China.
Xiaoming HuDepartment of Orthopedics, Guangdong Key Lab of Orthopedic Technology and Implant, Key Laboratory of Trauma & Tissue Repair of Tropical Area of PLA, Guangzhou General Hospital of Guangzhou Military Command of PLA, 111 Liuhua Road, Guangzhou, Guangdong, 510010, China.
Yu ZhangDepartment of Orthopedics, Guangdong Key Lab of Orthopedic Technology and Implant, Key Laboratory of Trauma & Tissue Repair of Tropical Area of PLA, Guangzhou General Hospital of Guangzhou Military Command of PLA, 111 Liuhua Road, Guangzhou, Guangdong, 510010, China.
Mingying PengChina-Germany Research Center for Photonic Materials and Device, the State Key Laboratory of Luminescent Materials and Devices, School of Materials Science and Engineering, South China University of Technology, 381 Wushan Road, Guangzhou, 510641, China.
Hong XiaDepartment of Orthopedics, Guangdong Key Lab of Orthopedic Technology and Implant, Key Laboratory of Trauma & Tissue Repair of Tropical Area of PLA, Guangzhou General Hospital of Guangzhou Military Command of PLA, 111 Liuhua Road, Guangzhou, Guangdong, 510010, China.
Gang HanDepartment of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA, 01605, USA.ORCID 0000-0002-2300-5862
General Hospital of Guangzhou Military Command · CNSouth China University of Technology · CNUniversity of Massachusetts Chan Medical School · US

Funding

Wireless Optogenetics by relay nano-illuminatorsR01MH103133 · NIMH · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI HAN, GANG · 2013 to 2016
$1.3M
Optogenetic toolkit for remote control of voltage-gated calcium channelsR21GM126532 · NIGMS · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI HAN, GANG, ZHOU, YUBIN · 2018 to 2019
$443k
NIGMS NIH HHS R21 GM126532NIH HHS R01MH103133NIH HHS R21GM126532NIMH NIH HHS R01 MH103133
6 · The paper itself

Abstract

Despite its 5-year event-free survival rate increasing to 60-65% due to surgery and chemotherapy, osteosarcoma (OS) remains one of the most threatening malignant human tumors, especially in young patients. Therefore, a new approach that combines early diagnosis with efficient tumor eradication and bioimaging is urgently needed. Here, a new type of mesoporous silica-coated bismuth sulfide nanoparticles (Bi

Indexed as

AnimalsApoptosisBismuthCell Line, TumorDoxorubicinMiceMice, NudeNanoparticlesOligopeptidesOsteosarcomaPorosityRatsSilicon DioxideSulfidesTomography, X-Ray Computedarginyl-glycyl-aspartic acidBismuthbismuth sulfideDoxorubicinOligopeptidesSilicon DioxideSulfidesBi2S3@MSNmitochondrial apoptosis pathwayosteosarcomaphotothermal therapy-chemotherapyX-ray computed tomography

Identifiers

PMID30102469
PMCPMC6504251
OpenAlexW2887726842

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.