Evidence map›Paper›PMID 30102248›Full record

ArticlePhysiological measurement2018

ECG signal classification for the detection of cardiac arrhythmias using a convolutional recurrent neural network.

Zhaohan Xiong, Martyn P Nash, Elizabeth Cheng, Vadim V Fedorov, Martin K Stiles, Jichao Zhao

Registry-linked trialOpen access · greenAbstract readEvaluation Study
In one paragraph

Article in Physiological measurement, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03662802 (Development of a Novel Convolution Neural Network for Arrhythmia Classification for Shockable Cardiac Rhythms), which is not on this map. Cited by 43 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
14.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03662802 completednot on this map

Development of a Novel Convolution Neural Network for Arrhythmia Classification for Shockable Cardiac Rhythms

Typeobservational_patient_registrySponsorScripps ClinicRan2018 to 2020Enrolled25,458ConditionsArrhythmias, Cardiac, Cardiac Arrest, Cardiac ArrythmiasArmsNeural Network Classifier
3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 1 synthesis or guideline pooled it, 160 citations in OpenAlex.

  1. Pooled it
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  12. A Review of Recurrent Neural Network-Based Methods in Computational Physiology.IEEE transactions on neural networks and learning systems · 2023
    Review
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  18. Artificial intelligence opportunities in cardio-oncology: Overview with spotlight on electrocardiography.American heart journal plus : cardiology research and practice · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Zhaohan XiongAuckland Bioengineering Institute, University of Auckland, Auckland, New Zealand.
Martyn P NashAuckland Bioengineering Institute, University of Auckland, Auckland, New Zealand.
Elizabeth ChengAuckland Bioengineering Institute, University of Auckland, Auckland, New Zealand.
Vadim V FedorovDepartment of Physiology and Cell Biology, The Ohio State University Wexner Medical Center, Columbus, OH 43210-1218, United States of America.
Martin K StilesSchool of Medicine, University of Auckland, Auckland, New Zealand.
Jichao ZhaoAuckland Bioengineering Institute, University of Auckland, Auckland, New Zealand.ORCID 0000-0003-3303-0401
University of Auckland · NZThe Ohio State University Wexner Medical Center · US

Funding

Targeting the Arrhythmogenic Sources of Human Atrial FibrillationR01HL135109 · NHLBI · OHIO STATE UNIVERSITY · PI Vadim V Fedorov · 2017 to 2026
$6.0M
Integration of structure and signaling in cardiac pacemaker functionR01HL115580 · NHLBI · OHIO STATE UNIVERSITY · PI FEDOROV, VADIM V · 2013 to 2021
$4.2M
NHLBI NIH HHS R01 HL115580NHLBI NIH HHS R01 HL135109
6 · The paper itself

Abstract

objectiveThe electrocardiogram (ECG) provides an effective, non-invasive approach for clinical diagnosis in patients with cardiac diseases such as atrial fibrillation (AF). AF is the most common cardiac rhythm disturbance and affects ~2% of the general population in industrialized countries. Automatic AF detection in clinics remains a challenging task due to the high inter-patient variability of ECGs, and unsatisfactory existing approaches for AF diagnosis (e.g. atrial or ventricular activity-based analyses). APPROACH: We have developed RhythmNet, a 21-layer 1D convolutional recurrent neural network, trained using 8528 single-lead ECG recordings from the 2017 PhysioNet/Computing in Cardiology (CinC) Challenge, to classify ECGs of different rhythms including AF automatically. Our RhythmNet architecture contained 16 convolutions to extract features directly from raw ECG waveforms, followed by three recurrent layers to process ECGs of varying lengths and to detect arrhythmia events in long recordings. Large 15  ×  1 convolutional filters were used to effectively learn the detailed variations of the signal within small time-frames such as the P-waves and QRS complexes. We employed residual connections throughout RhythmNet, along with batch-normalization and rectified linear activation units to improve convergence during training. MAIN

resultsWe evaluated our algorithm on 3658 testing data and obtained an F SIGNIFICANCE: Potentially, our approach could aid AF diagnosis in clinics and be used for patient self-monitoring to improve the early detection and effective treatment of AF.

Indexed as

Neural Networks, ComputerArrhythmias, CardiacDiagnosis, Computer-AssistedElectrocardiographyHumansPattern Recognition, AutomatedSensitivity and Specificity

Identifiers

PMID30102248
PMCPMC6377428
OpenAlexW2887679614

What OpenQuestion holds

Textmetadata
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.