Evidence map›Paper›PMID 30101903›Full record

ArticleInternal medicine (Tokyo, Japan)2018

Pancreatic Acinar Cell Carcinoma with Multiple Liver Metastases Effectively Treated by S-1 Chemotherapy.

Naoki Yoshida, Atsushi Kanno, Atsushi Masamune, Tatsuhide Nabeshima, Seiji Hongo, Shin Miura, Tetsuya Takikawa, Shin Hamada, Kazuhiro Kikuta, Kiyoshi Kume and 2 more

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Naoki YoshidaDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Japan.
Atsushi KannoDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Japan.
Atsushi MasamuneDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Japan.
Tatsuhide NabeshimaDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Japan.
Seiji HongoDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Japan.
Shin MiuraDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Japan.
Tetsuya TakikawaDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Japan.
Shin HamadaDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Japan.
Kazuhiro KikutaDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Japan.
Kiyoshi KumeDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Japan.
Masamichi UenoDivision of Internal Medicine, Tohoku Medical and Pharmaceutical University Wakabayashi Hospital, Japan.
Tooru ShimosegawaDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 79-year-old woman was referred for pancreatic tail cancer with multiple liver metastases. The pancreatic tail tumor was diagnosed as acinar cell carcinoma (ACC) histologically by endoscopic ultrasound-guided fine-needle aspiration. Because of multiple liver metastases, S-1 chemotherapy was administered, resulting in a partial response to chemotherapy one year later. After approximately three years, liver atrophy and esophageal varices developed. We suspected S-1 as the cause of the liver cirrhosis. S-1 cessation minimized ascites and improved the esophageal varices. Although S-1 can potentially treat ACC, we should be watchful for liver cirrhosis caused by its long-term administration.

Indexed as

AgedAntimetabolites, AntineoplasticCarcinoma, Acinar CellDrug CombinationsEndoscopic Ultrasound-Guided Fine Needle AspirationFemaleHumansLiver NeoplasmsOxonic AcidPancreatic NeoplasmsTegafurAntimetabolites, AntineoplasticDrug CombinationsOxonic AcidS 1 (combination)Tegafuracinarchemotherapyliver cirrhosis

Identifiers

PMID30101903
PMCPMC6355402

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.