Evidence map›Paper›PMID 30101538›Full record

ReviewGenes, brain, and behavior2019

The other side of the coin: Hypersociability.

Miklos Toth

Open access · bronzeAbstract readReview
In one paragraph

Review in Genes, brain, and behavior, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 26 citations in OpenAlex.

  1. Neuromodulation of swarming behavior inProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Neuromodulation of Swarming Behavior inbioRxiv : the preprint server for biology · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Oxytocin Receptor Gene Polymorphism in Lactating Dogs.Animals : an open access journal from MDPI · 2021
    Article
  9. Article
  10. Article
  11. Review
  12. The neuroscience and genomics of social behavior.Genes, brain, and behavior · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Miklos TothDepartment of Pharmacology, Weill Cornell Medical College, New York, New York.ORCID 0000-0001-8545-6362
Cornell University · US

Funding

Non-Genetic Transmission of Genetic Risk: Mechanism and Relevance to PsychiatricR01MH086883 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI TOTH, MIKLOS · 2009 to 2012
$1.3M
Epigenomic hotspots linking environmental adversity & stress to psychopathologyR01MH103102 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI TOTH, MIKLOS · 2013 to 2016
$1.3M
Maternal adversity and epigenetic and behavioral programming across generationsR01MH100894 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI TOTH, MIKLOS · 2013 to 2014
$1.2M
NIMH NIH HHS 5R01 MH086883NIMH NIH HHS R01 MH086883NIMH NIH HHS R01 MH100894NIMH NIH HHS R01 MH103102
6 · The paper itself

Abstract

Affiliative social motivation and behavior, that is, sociability that includes attachment, prosocial behavior (sharing, caring and helping) and empathy (the ability to understand and share the feelings of others), has high variability in the human population, with a portion of people outside of the normal range. While psychiatric disorders and autism spectrum disorders are typically associated with a deficit in social behavior, the opposite trait of hypersociability and indiscriminate friendliness are exhibited by individual with specific neurodevelopmental disorders and following early adverse care. Here we discuss both genetic and environmental factors that cause or increase the risk for developing pathological hypersociability from human to rodent models.

Indexed as

Polymorphism, GeneticSocial BehaviorAnimalsBrainDiscrimination, PsychologicalGene-Environment InteractionHumansInhibition, Psychologicalamygdalachild maltreatmentfriendlinesshypersociabilityindiscriminateinstitutional rearingneurodevelopmental diseasesocial behaviorsocial reward/aversionsynaptic genesWilliams syndrome

Identifiers

PMID30101538
PMCPMC6342648
OpenAlexW2886061301

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.